N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker designed for the assembly of PROTAC molecules. Its azide functionality allows for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-bearing compounds. Additionally, it is suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononynes (BCN), facilitating precise biomolecular conjugation. This reagent is pivotal for advancing drug development and targeted protein degradation research.
N-Methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy3 is a PEG-based PROTAC linker designed for the assembly of PROTAC molecules. Its azide functionality allows for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-bearing compounds. Additionally, it is suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononynes (BCN), facilitating precise biomolecular conjugation. This reagent is pivotal for advancing drug development and targeted protein degradation research.
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