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Fmoc-N-amido-PEG5-azide

PROTAC Linkers

Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker designed for use in the synthesis of PROTAC compounds. This reagent features an azide moiety that enables it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it is capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified entities, making it a versatile tool for bioconjugation and chemical biology applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2924480-17-9
Applications	PROTAC Linkers
Formula	C₂₇H₃₆N₄O₇
Molecular Weight	528.60
SMILES	O=C(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])OCC1C2=C(C3=C1C=CC=C3)C=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.