m-PEG10-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring an azide functional group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, as well as those with DBCO or BCN groups. This versatile reagent is essential for the assembly of complex bioconjugates, facilitating targeted protein degradation research and advancing drug discovery applications.
m-PEG10-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Featuring an azide functional group, it participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, as well as those with DBCO or BCN groups. This versatile reagent is essential for the assembly of complex bioconjugates, facilitating targeted protein degradation research and advancing drug discovery applications.
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