Methyltetrazine-amido-PEG7-azide is a PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules that have dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups, making it a versatile tool in chemical biology and drug development.
Methyltetrazine-amido-PEG7-azide is a PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it is suitable for strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules that have dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups, making it a versatile tool in chemical biology and drug development.
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