Fig. 1 · Structure
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m-PEG8-azide
PROTAC Linkers
m-PEG8-azide is a PEG-based linker specifically designed for PROTAC synthesis. This compound features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, m-PEG8-azide is suitable for strain-promoted alkyne-azide cycloaddition (SPAAC) when used with DBCO or BCN groups. Its versatile reactivity makes it a valuable tool for researchers engaged in targeted protein degradation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 869718-80-9 |
| Applications | PROTAC Linkers |
| Formula | C17H35N3O8 |
| Molecular Weight | 409.48 |
| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.