Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
tert-Butyl ([1,4'-bipiperidin]-4-ylmethyl)carbamate serves as a PROTAC linker, facilitating the design and synthesis of PROTACs for targeted protein degradation. This compound plays a crucial role in the development of innovative therapeutic strategies by enabling the selective modulation of protein levels within cells. Its application is valuable in the study of cellular processes and the development of treatments for various diseases through targeted approaches. -
PROTAC Linker
m-PEG3-Hydrazide is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTAC molecules. This compound enhances the solubility and stability of PROTACs, facilitating the targeted degradation of specific proteins via the ubiquitin-proteasome system. Its application in chemical biology allows researchers to effectively investigate protein interactions and functional mechanisms, thereby advancing therapeutic development and drug discovery efforts. -
PROTAC Linker
Decanedioic acid ammonium serves as a PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure enhances the selective degradation of target proteins, thereby advancing research in targeted protein modulation. This compound is essential for studies aiming to explore protein function and therapeutic applications in disease contexts. -
PROTAC Linker
13-Methoxy-13-oxotridecanoic acid serves as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound contributes to targeted protein degradation by connecting E3 ligases to target proteins, thus enhancing the specificity of cellular degradation processes. Its application is instrumental in drug discovery and the study of protein interactions, making it a valuable tool for researchers in the field of chemical biology. -
PROTAC Linker
Ethyl 2-(hydroxymethyl)cyclopropanecarboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound allows for effective conjugation of target proteins to E3 ligases, enhancing targeted protein degradation and the study of protein functions. Its chemical structure supports the creation of novel therapeutic strategies in various biological research applications. -
PROTAC Linker
Alkyne-PEG4-I is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its alkyne functionality facilitates the formation of stable covalent bonds, enabling efficient engagement of target proteins for degradation. This linker is integral for researchers investigating targeted protein degradation pathways and developing novel therapeutic agents. -
PROTAC Linker
1-Boc-4-(4-Cyanobenzyl)piperazine serves as a PROTAC linker, facilitating the development of targeted protein degradation strategies. This compound plays a pivotal role in the synthesis of PROTACs, enabling efficient recruitment of E3 ligases to specific substrate proteins. Its utility in bioconjugation applications and cellular studies makes it a valuable tool for researchers investigating protein ubiquitination and degradation mechanisms. -
PROTAC Linker
Benzyl (3-aminopropyl)(methyl)carbamate hydrochloride serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is crucial for the synthesis of selective degraders, enhancing targeted protein degradation in biological research. Its applications extend to studies in cellular signaling, cancer therapeutics, and other areas of drug discovery. -
PROTAC Linker
Trt-PEG4-C2-COOH is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features a PEG4 spacer that enhances solubility and flexibility in the resultant PROTAC molecules. It is suitable for applications in targeted protein degradation studies, enabling researchers to investigate novel therapeutic strategies in various disease models. -
PROTAC Linker
tert-Butyl (azetidin-3-ylmethyl)carbamate oxalate serves as a versatile PROTAC linker promoting targeted protein degradation. This compound facilitates the assembly of PROTACs, enabling the selective modulation of protein levels within cellular systems. Its application is critical in expanding the toolkit for researchers engaged in the development of targeted therapies. -
PROTAC Linker
Dibenzyl adipate is a versatile PROTAC linker utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). Its structural properties facilitate the development of compounds that can recruit E3 ligases for targeted protein degradation. This compound is instrumental in studying protein dynamics and therapeutic interventions in various diseases, including cancer. -
PROTAC Linker
10-Bromo-1-aminodecane, Hydrobromide serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for linking target proteins to E3 ligases, thus enhancing targeted protein degradation. Its unique structure enables efficient synthesis and optimization of PROTACs for various research applications, particularly in investigating protein interactions and cellular pathways. -
PROTAC Linker
Sulfonic chloride-C4-COOMe is a versatile PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the formation of targeted protein-degradation complexes, enabling the selective degradation of specific proteins within the cell. It is valuable in research applications focusing on targeted therapeutics and the exploration of protein function through modulation. -
PROTAC Linker
N1-Methylbutane-1,4-diamine is a versatile PROTAC linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation strategies by linking E3 ligases to specific target proteins. Its application is critical in advancing research in cellular signaling and therapeutic interventions targeting disease-related proteins. -
PROTAC Linkers
Amino-PEG14-alcohol is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the coupling of target proteins with E3 ligases, thereby promoting targeted protein degradation. Its high solubility and biocompatibility make it suitable for a wide range of biological applications in drug discovery and development. -
PROTAC Linker
BnO-PEG3-Br is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This chemical reagent facilitates the conjugation of protein targets and E3 ligases, enhancing the selective degradation of target proteins. Its application in research supports investigations into targeted protein degradation mechanisms and drug discovery initiatives. -
PROTAC Linker
tert-Butyl 4-(3-hydroxyprop-1-yn-1-yl)piperidine-1-carboxylate serves as an effective PROTAC linker. Its primary function is to facilitate the development of proteolysis-targeting chimeras (PROTACs), which enhance targeted protein degradation pathways. This compound is essential for studies aimed at optimizing PROTAC design and investigating protein homeostasis in cellular models. -
PROTAC Linker
NH2-spiro[3.3]heptane-methyl formate is a versatile PROTAC linker designed for the efficient synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of targeted protein degradation mechanisms, enabling researchers to manipulate protein levels within cells. Its unique structural characteristics make it an essential tool for studying protein interactions and degradation pathways in various biological contexts. -
PROTAC Linker
Methyl 3-((tert-butoxycarbonyl)(methyl)amino)propanoate is a PROTAC linker that facilitates the development of protein-targeting chimeras. This compound plays a crucial role in the synthesis of PROTACs, enabling the targeted degradation of specific proteins. It is valuable for research applications focused on understanding protein regulation and therapeutic development through targeted protein degradation. -
PROTAC Linker
trans-Cyclobutane-1,3-dicarboxylic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in synthesizing novel therapeutic agents that selectively degrade target proteins. Its unique structural properties enable effective binding and modulation of biological pathways, making it a valuable tool for research in drug discovery and targeted protein degradation studies. -
PROTAC Linker
tert-Butyl 2-(2-aminoethyl)-2,7-diazaspiro[3.5]nonane-7-carboxylate dihydrochloride functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the effective conjugation of E3 ligase recruiters to target proteins, enhancing targeted protein degradation for research applications in cellular biology and drug discovery. Its unique structural properties provide versatility in the design of innovative therapeutic strategies aimed at modulating protein levels in various biological contexts. -
PROTAC Linker
tert-Butyl (6-aminohexyl)carbamate hydrochloride functions as a PROTAC linker essential for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the formation of targeted degradation complexes by linking E3 ligases to substrate proteins, thereby enhancing the selective removal of specific proteins within cellular systems. It is valuable for research applications in targeted protein degradation and the development of novel therapeutics. -
PROTAC Linker
NH2-C3-PEG2-NH2 is a polyethylene glycol (PEG) based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the assembly of PROTACs by connecting target proteins to E3 ligases, enabling targeted protein degradation. Its versatile structure supports a range of research applications in drug discovery and therapeutic development, particularly in studies focused on protein regulation and degradation pathways. -
PROTAC Linker
1,4-Benzenediethanol serves as a crucial PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. This compound enables the efficient conjugation of ligands to E3 ligases, enhancing the selectivity and efficacy of protein degradation. It is an essential tool for researchers focusing on innovative therapeutic strategies in oncology and cellular regulation. -
PROTAC Linker
Ethyl hept-6-ynoate serves as a PROTAC linker, facilitating the creation of proteolysis-targeting chimeras (PROTACs). This compound enhances the structural diversity and efficacy of PROTACs by serving as a crucial molecular bridge. Its applications are relevant in targeted protein degradation studies and therapeutic research, enabling investigations into protein function and regulation in a variety of biological contexts. -
PROTAC Linker
2-(1-Benzylpiperidin-4-yl)acetic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is integral in the synthesis of innovative therapeutic agents aimed at enhancing targeted protein degradation. Its application is particularly relevant in drug discovery and development, providing researchers with a valuable tool in the study of protein homeostasis and regulation. -
PROTAC Linker
Tert-butyl (2-(2-(methylamino)ethoxy)ethyl)carbamate hydrochloride functions as a PROTAC linker, facilitating the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enables the targeted degradation of specific proteins, offering a powerful approach in drug discovery and therapeutic development. Its application extends to studying protein interactions and cellular pathways, making it a valuable tool in chemical biology research. -
PROTAC Linker
tert-Butyl 19-bromononadecanoate serves as a PROTAC linker, facilitating the development of targeted protein degradation strategies. Its unique structural properties enhance the efficacy of PROTAC molecules by enabling effective recruitment of E3 ligases to specific target proteins. This compound is essential for researchers engaged in the synthesis of PROTACs aimed at manipulating cellular pathways for therapeutic applications. -
PROTAC Linker
Benzyl (6-aminohexyl)carbamate is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by enabling the conjugation of E3 ligases and ligand-binding domains. Its application is critical in research aimed at developing innovative therapeutic strategies for cancer and various diseases through targeted protein degradation. -
PROTAC Linker
Mal-PEG5-mal is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ubiquitin ligases, enabling targeted protein degradation. Mal-PEG5-mal is essential for researchers developing novel therapeutic strategies through the modulation of protein levels in various biological contexts. -
PROTAC Linker
tert-Butyl 2-azaspiro[3.3]heptan-6-ylcarbamate oxalate(2:1) is a PROTAC linker designed for use in the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the binding of target proteins to E3 ligases, enabling selective degradation pathways. Its application in drug discovery supports the exploration of targeted protein modulation for therapeutic interventions. -
PROTAC Linker
Methyl 15-bromopentadecanoate is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases to target proteins, allowing for targeted degradation in cellular systems. Its application is significant in drug discovery and development, particularly in the study of protein homeostasis and therapeutic interventions for various diseases. -
PROTAC Linker
2,5-Dioxopyrrolidin-1-yl 2-(2-(prop-2-yn-1-yloxy)ethoxy)acetate serves as a highly functional PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the targeted degradation of specific proteins through ubiquitin-proteasome pathways. It is essential for researchers focused on developing selective protein degraders in therapeutic applications, particularly in cancer and other diseases driven by aberrant protein levels. -
PROTAC Linker
Fmoc-NH-CH2-PEG3-C2-NH2 hydrochloride is a versatile PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of target proteins with E3 ubiquitin ligases, promoting selective degradation of the intended targets. It is particularly valuable in studies related to targeted protein degradation and the development of innovative therapeutic strategies. -
PROTAC Linker
4-(Triethylsilyl)but-3-yn-1-ol serves as a versatile linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs). Its unique chemical structure allows for effective conjugation to target proteins and E3 ligases, facilitating targeted degradation within cellular systems. This compound is instrumental in advancing research in targeted protein degradation and drug discovery applications. -
PROTAC Linker
tert-Butyl 3-((4-formylphenyl)thio)azetidine-1-carboxylate is a PROTAC linker designed for the synthesis of targeted protein degradation agents. This compound facilitates the formation of heterobifunctional molecules that can selectively degrade specific target proteins through the ubiquitin-proteasome system. Its unique structure allows for the effective modular design of PROTACs, enhancing the versatility and efficacy in drug discovery and research applications focused on therapeutic development. -
PROTAC Linker
N-Methyl-N'-(hydroxy-PEG2)-Cy5 is a PEG-based PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the solubility and biocompatibility of PROTACs, enabling effective targeting and degradation of specific proteins within cellular environments. Its strategic application is particularly valuable in drug discovery and the development of novel therapeutic strategies aimed at selective protein modulation. -
PROTAC Linker
tert-Butyl (6-azaspiro[3.4]octan-2-yl)carbamate hydrochloride is a PROTAC linker designed for the development of targeted protein degradation molecules. This compound facilitates the conjugation of protein degradation agents, enabling the selective ubiquitination and subsequent proteasomal degradation of specific target proteins. Its application in synthetic biology and drug discovery enhances the potential of PROTAC technology in therapeutic development. -
PROTAC Linker
tert-Butyl 6-benzyl-2,6-diazaspiro[3.4]octane-2-carboxylate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the targeted degradation of specific proteins, enhancing the precision of therapeutic interventions in various diseases. Its unique chemical structure enables effective conjugation with protein ligands, making it a valuable tool in chemical biology and drug discovery research. -
PROTAC Linker
2-Azaspiro[3.5]nonan-7-ol is a specific linker utilized in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the recruitment of E3 ubiquitin ligases to target proteins, enabling targeted degradation pathways. Its strategic incorporation into PROTAC constructs promotes selective cellular activity, making it valuable for research applications aimed at elucidating protein function and developing therapeutic agents. -
PROTAC Linker
Cis-3-(Methoxycarbonyl)cyclobutanecarboxylic acid is a versatile PROTAC linker that facilitates the development of PROTAC molecules for targeted protein degradation. Its unique structural properties enhance cellular permeability and proteolytic efficacy. This compound is valuable for research applications focusing on targeted therapeutics and the modulation of protein interactions within cellular pathways. -
PROTAC Linker
4-(Aminomethyl)bicyclo[2.2.2]octane-1-carboxylic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound provides a versatile scaffold for conjugating ligands, enabling selective degradation of target proteins. Applications include targeted protein degradation studies and drug discovery in the realm of cancer therapeutics. -
PROTAC Linker
trans-Ethyl (1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylate hydrochloride functions as a PROTAC linker, facilitating targeted protein degradation by promoting the formation of a ternary complex between an E3 ligase and a target protein. This compound is instrumental in the synthesis of PROTACs, enabling the development of novel therapeutic strategies by selectively degrading specific proteins of interest in cancer and other diseases. Its unique structural properties make it a valuable tool for researchers exploring protein modulation and degradation pathways. -
PROTAC Linker
1-Ethyl trans-1,4-cyclohexanedicarboxylate is a versatile PROTAC linker designed for the effective synthesis of PROTACs. This compound facilitates the development of targeted protein degradation strategies, enabling the selective degradation of specific proteins within cellular systems. Its unique structural properties make it suitable for various biological applications in chemical biology and drug discovery research. -
PROTAC Linker
Fmoc-C-PEG3-C3-Succinamic acid is a PROTAC linker designed to facilitate the development of proteolysis targeting chimeras (PROTACs). This compound enhances the solubility and stability of PROTACs, promoting effective target protein degradation. Its unique structure supports the efficient conjugation of target ligands and E3 ligase recruiters, making it valuable in anti-cancer research and other therapeutic applications. -
PROTAC Linker
Bn-PEG2-Br is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligase recognition elements, enabling selective degradation of target proteins through the ubiquitin-proteasome pathway. Bn-PEG2-Br serves as a crucial tool in drug discovery and development, expanding research into targeted protein degradation strategies. -
PROTAC Linker
3-(Cbz-aminomethyl)azetidine hydrochloride functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is crucial in creating bifunctional molecules that promote targeted protein degradation, offering significant potential in therapeutic applications for various diseases. Its role in PROTAC synthesis makes it an essential reagent for researchers focused on innovative drug development. -
PROTAC Linker
4,4'-(Butane-1,4-diylbis(oxy))dianiline functions as a PROTAC linker, facilitating the development of targeted protein degradation technologies. This compound plays a critical role in the synthesis of PROTAC molecules, which harness the ubiquitin-proteasome system for selective degradation of intracellular proteins. Its application is essential in advancing research in drug discovery and therapeutic strategies aimed at modulating protein levels in various diseases. -
PROTAC Linkers
Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the formation of linkages between target proteins and E3 ligases, promoting targeted degradation through the ubiquitin-proteasome system. It is essential for advancing research in protein degradation and developing innovative therapeutic strategies. -
PROTAC Linker
6-(Methylamino)hexan-1-ol is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure facilitates the effective conjugation of target proteins, enhancing the development of novel therapeutic agents through targeted protein degradation. This compound plays a crucial role in advancing research in targeted drug discovery and molecular biology applications.
