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CRBN ligand-869

Ligand for E3 Ligase

CRBN ligand-869 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of this protein for targeted protein degradation. This compound can be conjugated with a ligand specific to the target protein through a suitable linker to create a PROTAC (proteolysis-targeting chimera). CRBN ligand-869 is valuable for research applications in protein modulation and therapeutic discovery.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3052750-93-0
Applications	Ligand for E3 Ligase
Formula	C₂₁H₂₃F₃N₄O₆
Molecular Weight	484.43
SMILES	O=CC1CCN(C2=CC=C3C(=C2)N(C(=O)N3C4C(=O)NC(=O)CC4)C)CC1.O=C(O)C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.