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CRBN ligand-193

Ligand for E3 Ligase

CRBN ligand-193 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC). It is instrumental in studies aiming to harness targeted protein degradation as a therapeutic strategy. The application of CRBN ligand-193 advances research in drug development and cellular regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3031608-15-5
Applications	Ligand for E3 Ligase
Formula	C₂₀H₂₆FN₃O₂
Molecular Weight	359.45
SMILES	O=C1NC(=O)C(C2=CC=C(C(F)=C2)N3CCC4(CCNCC4)CC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.