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CRBN ligand-314

Ligand for E3 Ligase

CRBN ligand-314 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN for targeted protein degradation. This compound can be combined with a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera), a valuable tool in the study of protein function and turnover in cellular processes. Its applications include research on targeted therapy and novel drug development strategies in oncology and other disease areas.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925082-63-7
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₁N₅O₂
Molecular Weight	257.25
SMILES	O=C1NC(=O)CCN1C2=CC=C(N)C=3C=NN=CC32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.