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CRBN ligand-339

Ligand for E3 Ligase

CRBN ligand-339 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. It can be utilized to construct PROTACs (Proteolysis Targeting Chimeras) when linked to a specific target protein ligand via a suitable linker. This compound plays a critical role in targeted protein degradation research, enabling studies on ubiquitination and protein turnover.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925099-89-2
Applications	Ligand for E3 Ligase
Formula	C₁₁H₉BrN₄O₂
Molecular Weight	309.12
SMILES	O=C1NC(=O)CCN1C2=CC=C(Br)C=3C=NNC32

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.