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CRBN ligand-164

Ligands for E3 Ligase

CRBN ligand-164 is a selective ligand for the CRBN E3 ubiquitin ligase, facilitating the ubiquitination of target proteins. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras), which harness the ubiquitin-proteasome system to selectively degrade proteins of interest. Its ability to induce targeted protein degradation makes CRBN ligand-164 valuable in drug discovery and therapeutic research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3036607-71-0
Applications	Ligands for E3 Ligase
Formula	C₁₃H₁₄BrNO₂
Molecular Weight	296.16
SMILES	O=C(C(C1=C(C)C=C(Br)C=C1C)CC2)NC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.