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CRBN ligand-265

Ligand for E3 Ligase

CRBN ligand-265 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this crucial protein. Its design enables the conjugation with target protein ligands through a linker, thereby allowing for the formation of PROTACs (proteolysis-targeting chimeras). This compound is valuable in studies focusing on targeted protein degradation and the modulation of specific cellular pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925089-18-3
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₀BrN₃O₂
Molecular Weight	320.15
SMILES	O=C1NC(=O)CCN1C=2C=CC3=NC=C(Br)C=C3C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.