CRBN ligand-885 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to target protein ligands through a linker to create proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation. Its application is crucial in the study of protein homeostasis and the modulation of various cellular pathways.
CRBN ligand-885 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to target protein ligands through a linker to create proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation. Its application is crucial in the study of protein homeostasis and the modulation of various cellular pathways.
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