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CRBN ligand-356

Ligand for E3 Ligase

CRBN ligand-356 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be utilized in the development of PROTACs (Proteolysis Targeting Chimeras) by linking it to a target protein ligand through a suitable linker. Its key biological activity makes it valuable for research in targeted protein degradation and therapeutic applications in various diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925090-58-8
Applications	Ligand for E3 Ligase
Formula	C₁₂H₉ClN₄O₂
Molecular Weight	276.68
SMILES	O=C1NC(=O)CCN1C2=CC=C3N=C(Cl)N=CC3=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.