CRBN ligand-639 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand using a linker to create a proteolysis-targeting chimera (PROTAC). CRBN ligand-639 is instrumental in elucidating ubiquitin-mediated protein degradation pathways and has applications in targeted protein degradation research.
CRBN ligand-639 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand using a linker to create a proteolysis-targeting chimera (PROTAC). CRBN ligand-639 is instrumental in elucidating ubiquitin-mediated protein degradation pathways and has applications in targeted protein degradation research.
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