CRBN ligand-110

Catalog No.: A80857
Ligands for E3 Ligase
CRBN ligand-110 serves as a selective ligand for the CRBN E3 ubiquitin ligase, facilitating the development of PROTAC (Proteolysis Targeting Chimeras). Its integration into PROTAC designs allows for targeted degradation of specific proteins, making it a valuable tool in drug discovery and therapeutic research. This compound is instrumental in exploring novel approaches to modulate protein levels and activity in cellular systems.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Nature Volume 622 Issue 7982 (2023)
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Biological Activity
DescriptionCRBN ligand-110 serves as a selective ligand for the CRBN E3 ubiquitin ligase, facilitating the development of PROTAC (Proteolysis Targeting Chimeras). Its integration into PROTAC designs allows for targeted degradation of specific proteins, making it a valuable tool in drug discovery and therapeutic research. This compound is instrumental in exploring novel approaches to modulate protein levels and activity in cellular systems.
Product Information
Catalog NumA80857
FormulaC11H8BrClFNO2
Molecular Weight320.54
CAS Number2924092-72-6
SMILESO=C(C(C1=CC(F)=C(Br)C=C1Cl)CC2)NC2=O
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