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CRBN ligand-110

Ligands for E3 Ligase

CRBN ligand-110 serves as a selective ligand for the CRBN E3 ubiquitin ligase, facilitating the development of PROTAC (Proteolysis Targeting Chimeras). Its integration into PROTAC designs allows for targeted degradation of specific proteins, making it a valuable tool in drug discovery and therapeutic research. This compound is instrumental in exploring novel approaches to modulate protein levels and activity in cellular systems.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2924092-72-6
Applications	Ligands for E3 Ligase
Formula	C₁₁H₈BrClFNO₂
Molecular Weight	320.54
SMILES	O=C(C(C1=CC(F)=C(Br)C=C1Cl)CC2)NC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.