CRBN ligand-699

Catalog No.: A80904
Ligand for E3 Ligase
CRBN ligand-699 is a small molecule ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of the CRBN protein, enabling targeted degradation of specific proteins when linked to a target protein ligand through a suitable linker. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras) for research applications focused on ubiquitin-mediated protein turnover and targeted therapy strategies.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-699 is a small molecule ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of the CRBN protein, enabling targeted degradation of specific proteins when linked to a target protein ligand through a suitable linker. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras) for research applications focused on ubiquitin-mediated protein turnover and targeted therapy strategies.
Product Information
Catalog NumA80904
FormulaC14H16N4O3
Molecular Weight288.31
CAS Number2925074-73-1
SMILESO=C1NC(=O)CCN1C2=CC=C3C(=O)N(CC3=C2)CCN
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