Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
GSK-1562590 is a high-affinity antagonist of the uropeptide-II receptor, demonstrating notable selectivity. This compound exhibits significant antagonistic activity across various biological assays and maintains prolonged receptor binding. GSK-1562590 effectively inhibits human urinary peptide-II-induced aortic contraction in rat models, with effects persisting for a minimum of 24 hours. Its properties make it a valuable tool for investigating the role of uropeptide-II in cardiovascular physiology and related metabolic research. -
Leukotriene
Leukotriene C4 methyl ester is a metabolic derivative of leukotriene C4, primarily functioning as a potent mediator in inflammatory responses. It exhibits significant biological activity in promoting vascular permeability and bronchoconstriction, making it relevant for studying a variety of inflammatory conditions. This compound is particularly useful for research focused on psoriasis and other related dermatological disorders, facilitating the exploration of leukotriene signaling pathways. -
Flavonol
Kaempferol 3-O-alpha-L-(2, 3-di-Z-p-coumaroyl) rhamnoside is a flavonol compound derived from Platanus occidentalis. This compound exhibits significant inhibitory activity against alpha-amylase and DPP IV, making it suitable for research applications focused on carbohydrate metabolism and diabetes-related studies. Its unique structure and biological properties position it as a valuable tool in investigating the therapeutic potential of flavonoids in metabolic disorders. -
Endogenous Metabolite
1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol is a triglyceride characterized by its unique structural composition and distribution in biological matrices. This endogenous metabolite has been identified in human milk, infant formulas, various mammalian milks, and certain vegetable oils, providing insights into its potential role in nutrition and metabolism. Research applications include studying lipid metabolism, evaluating dietary sources of essential fats, and investigating the health benefits associated with triglycerides in human development. -
Fungal Metabolite
Butyrolactone II is a fungal metabolite derived from Aspergillus flavipes, known for its activity as a biosynthetic precursor. It exhibits significant biological activity, particularly in the regulation of secondary metabolites and has been identified for its role in modulating fungal growth. This compound is primarily utilized in research applications studying fungal biology, metabolic pathways, and the development of antifungal strategies. -
Stable Isotope
H-Abu-OH-d2 is a deuterium-labeled form of H-Abu-OH, one of the three isomers of aminobutyric acid. This compound serves as a stable isotope used in various biochemical studies and is particularly relevant in metabolic research. It has been observed to be elevated in the plasma of patients with conditions such as Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency, making it valuable for clinical investigations. -
Sex Pheromone
Methyl 7(Z)-hexadecenoate is a sex pheromone primarily associated with Trogoderma glabrum. This compound is known to induce attractive and sexually stimulating responses in male specimens of the species. It serves as a valuable tool for research into insect behavior, pheromone communication, and ecological interactions within entomological studies. -
Endogenous Metabolite
Linoleoyl-L-carnitine chloride is an endogenous metabolite that functions as a long-chain acylcarnitine. It has been shown to exhibit significant biological activity, particularly in lipid metabolism and energy homeostasis. Research applications include studies on metabolic dysregulation and the pharmacological effects of compounds like isoniazid, which can elevate hepatic levels of linoleoyl-L-carnitine in murine models at high doses. -
Endogenous Metabolite
Conicasterol is a 4-mercaptosteroid known for its significant cytotoxic activity against cancer cells. It exhibits an IC50 value of 6.23 μg/mL in human breast adenocarcinoma cell line (MCF-7), indicating strong potential for antitumor applications. This compound may serve as a valuable bioactive lead molecule in cancer research and therapeutic development. -
Endogenous Metabolite
1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol is an endogenous metabolite primarily associated with triglyceride composition. It plays a vital role in lipid metabolism and has been utilized in research to analyze the triglyceride profiles within bovine milk fat. The compound has been characterized through various chromatographic techniques, contributing to the identification of a diverse array of triglycerides in biological samples. -
Endogenous Metabolite
Demethyl PL265 is a selective dual ENKephalinase inhibitor (DENKi) targeting the enzymatic breakdown of endogenous enkephalins. This compound demonstrates significant potential in alleviating pain through the modulation of endogenous opioid signaling pathways. Its ability to enhance enkephalin levels may provide valuable insights into pain management strategies and the study of opioid-related mechanisms in neurobiology. -
Endogenous Metabolite
NPE-caged-proton functions as a caged proton donor that releases protons upon exposure to UV light. This reagent enhances the activity of the fusion protein GP64 under mildly acidic conditions, facilitating the interaction of enveloped viruses with liposome membranes comprised of acidic phospholipids at pH levels ranging from 4.0 to 5.5. Utilized in viral membrane fusion studies, NPE-caged-proton serves as an essential tool for investigating viral behavior and interactions in diverse chemical and biochemical environments. -
α-glucosidase
2,3-Indolobetulin is a pentacyclic triterpene and a derivative of betulin that acts as an α-glucosidase inhibitor. This compound demonstrates significant biological activity in modulating carbohydrate metabolism and is applicable in research focused on diabetes management and glycemic control. Its potential as a therapeutic agent in glucose regulation makes it valuable for studies on metabolic disorders. -
Endogenous Metabolite
Glucoiberin potassium is an endogenous metabolite known for its role in modulating metabolic pathways. This compound exhibits biological activity that can influence glucose metabolism and insulin sensitivity. Research applications include studies on diabetes, metabolic disorders, and the evaluation of cellular response to dietary components. -
Endogenous Metabolite
4-Chloro-N,N-diisopropylbenzamide is an amide with significant relevance as a substrate for cytochrome P450 enzymes in vivo and for acetylcholinesterase in vitro. This compound plays a crucial role in metabolic studies, enabling the investigation of enzyme kinetics and substrate specificity. Its application extends to research focused on drug metabolism and neuropharmacology. -
Maltoamylase
Maltogenic amylase is an enzyme that targets maltoamylase, facilitating the hydrolysis of starch into shorter oligosaccharides. It exhibits significant biological activity in starch degradation and is instrumental in various biotechnological applications, including the food industry and biofuel production. Innovations in enzyme engineering enhance its reaction kinetics and substrate selectivity while allowing for activity modulation under varying pH conditions, enabling precise control in dynamic environments. -
Endogenous metabolite
13,14-EDT is an endogenous metabolite derived from oxylipids and adrenal acid, produced via the cytochrome P450 (CYP) enzymatic pathway. This compound is of significant interest in the study of lipid metabolism and related biological processes. It serves as a valuable tool for investigating the roles of CYP enzymes in metabolic pathways and their implications in various physiological conditions. -
Endogenous Metabolite
Methyl β-D-Galactopyranoside is an endogenous metabolite primarily involved in carbohydrate metabolism. This compound serves as a galactose donor and is utilized in various biological assays to study glycosylation processes and carbohydrate-binding proteins. Its role in cell signaling and metabolism makes it valuable for research applications focusing on glycobiology and cellular interactions. -
Endogenous Metabolite
Cedefingol is an endogenous metabolite that acts as an α-glucosidase inhibitor. This compound demonstrates antitumor properties and exhibits diverse bioactivities influenced by the fermentation time of dark tea samples. Additionally, cedefingol displays antioxidant activity, as evidenced by its effectiveness in the DPPH assay. Research applications include studies on metabolic pathways, enzymatic processes, and potential therapeutic effects in cancer research. -
Endogenous Metabolite
SSR180711 is a potent and subtype-selective agonist of the α7 nicotinic acetylcholine receptor. This compound demonstrates significant activity in the context of Alzheimer's disease and schizophrenia, making it valuable for research into cognitive function. Additionally, SSR180711 can be utilized to investigate intracerebral hemorrhage subtypes related to cerebral small vessel disease and is applicable in electrophysiological and behavioral studies focused on cerebrovascular lesions and their impacts. -
Endogenous Metabolite
Thromboxane B2 ethanolamide (TXB2-EA) is an endogenous metabolite derived from the hydrolysis of thromboxane A2 ethanolamide. It serves as a critical regulator in various physiological processes, including platelet function and vascular tone. TXB2-EA is useful in research focused on cardiovascular health and thrombotic disorders, providing insights into the roles of thromboxane signaling in health and disease. -
Endogenous Metabolite
Xanthosine-5'-monophosphate is an endogenous metabolite involved in nucleoside metabolism. It plays a role in the purine nucleotide cycle and has implications in various cellular processes. Xanthosine-5'-monophosphate is utilized in research applications related to metabolic pathways, enzyme activity studies, and the investigation of nucleotide signaling mechanisms. -
Endogenous Metabolite
(R)-3-Hydroxyisobutyric acid sodium is an endogenous metabolite associated with the metabolic disorder 3-hydroxyisobutyric aciduria, which is characterized by increased urinary levels of this compound. This reagent is instrumental in metabolic studies and can be used in research investigating metabolic pathways and associated disorders. Its utility in diagnosing metabolic abnormalities makes it an important tool in clinical and biochemical research. -
Endogenous Metabolite
9(S)-HODE cholesteryl ester is an endogenous metabolite associated with atherosclerotic lesions. Its structure contains an oxidized fatty acid component, likely derived from either enzymatic lipoxygenation or lipid peroxidation. This compound serves as a valuable standard for the analysis of chiral HODE cholesteryl esters, facilitating research into lipid metabolism and cardiovascular disease. -
Endogenous Metabolite
Rovicurt is a mixture of permethrin and tetramethrin that targets endogenous metabolites, demonstrating significant effects on reproductive physiology. It stimulates biological adaptation mechanisms, leading to an increase in the diameter of seminiferous tubules and the proliferation of Sertoli cells. Additionally, Rovicurt enhances the fertilizing ability of sperm, making it a valuable reagent for research in reproductive biology and environmental toxicology studies. -
Endogenous Metabolite
(Rac)-Terreic acid is a natural product that primarily inhibits mitotic kinase 8, a key regulator in cell division. With its capability to modulate cell signaling pathways, (Rac)-Terreic acid serves as a valuable bioactive molecule for studying the mechanisms of cell proliferation and survival. This compound is relevant for research applications focused on cellular dynamics and cancer biology. -
Pheromone
2-(Undecyloxy)ethanol is a pheromone primarily associated with the male Monochamus alternatus Hope. It plays a critical role in chemical communication and mating behaviors within its species. This compound is valuable for research applications focused on pheromone detection, behavior studies, and pest management strategies. -
Endogenous Metabolite
Carbonate Ionophore VII is a selective transporter for carbonate ions, facilitating their movement across lipid membranes. This compound is primarily employed in the development of ion-selective electrodes, enabling precise measurement of carbonate concentrations in various biological and environmental samples. Its application is crucial for studies involving cellular metabolism and physiological processes where carbonate ions play a significant role. -
Endogenous Metabolite
Diadenosine pentaphosphate pentaammonium is an endogenous vasoactive purine dinucleotide that serves as a crucial metabolite in cellular signaling. It is primarily found in platelet secretory vesicles and plays a significant role in the regulation of vascular tone and thrombocyte function. This compound is useful in research related to purinergic signaling, platelet activation, and neurobiology, providing insights into cellular communication mechanisms and potential therapeutic targets. -
Endogenous Metabolite
1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol is a triglyceride enriched with fatty acid esters of hydroxy fatty acids (FAHFAs) that serves as a significant intracellular reservoir of FAHFAs. This compound plays a crucial role in modulating cellular levels of FAHFAs, thereby influencing lipid metabolism and signaling pathways. Research applications include investigating triglyceride and FAHFAs metabolism, as well as understanding their implications in metabolic diseases and cellular homeostasis. -
Endogenous Metabolite
(±)20-HDHA is a racemic mixture and an autoxidation product of Docosahexaenoic acid (DHA). It is produced via peroxidation processes in human platelets and rat brain homogenate. This compound serves as an endogenous metabolite, making it relevant for research into lipid metabolism and the oxidative stress response in various biological systems. -
Endogenous Metabolite
D-Glyceric acid is an endogenous metabolite that plays a significant role in metabolic pathways. It is particularly valuable in research related to primary hyperoxaluria type I and glutaric acidemia type 2. Its presence in urine makes it a key biomarker for studying these metabolic disorders and aids in understanding the biochemical mechanisms underlying these conditions. -
Endogenous Metabolite
9α,11β-Prostaglandin F2α is an endogenous metabolite that plays a significant role in various physiological processes. It is primarily studied for its involvement in respiratory conditions, particularly asthma, where it may influence bronchial tone and inflammation. This compound offers vital insights into the mechanisms of asthma and related disorders, facilitating research into potential therapeutic strategies. -
Endogenous Metabolite
Phosphorylcholine chloride calcium salt tetrahydrate is an endogenous metabolite that plays a crucial role in cellular signaling and membrane integrity. This compound is involved in various biological processes, including cell proliferation and differentiation. It is utilized in research applications focusing on cell biology, neurobiology, and immunology, serving as a key component in studies related to lipid metabolism and membrane dynamics. -
Endogenous Metabolite
4-Methyl-1-phenyl-2-pentanone is an endogenous metabolite with potential implications in metabolic studies. This compound is involved in various biochemical pathways and may play a role in the regulation of neurochemical processes. Its application spans research areas such as pharmacology, biochemistry, and toxicology, where it can be utilized to investigate metabolic disorders and neuroactive substances. -
Endogenous Metabolite
Erythronic acid is an endogenous metabolite derived from carbohydrates, playing a crucial role in metabolic pathways. It is instrumental in investigating metabolic diseases, particularly in understanding hyperuricemia and its association with mitochondrial dysfunction, especially in cases of transaldolase deficiency. This compound serves as a valuable tool for researchers exploring the biochemical mechanisms underlying these conditions. -
Endogenous Metabolite
Cis-5-Tetradecenoic acid is an endogenous metabolite that plays a significant role in metabolic processes. It is useful for investigating Long Chain 3 Hydroxyacyl CoA Dehydrogenase Deficiency and its associated biochemical pathways. This compound serves as a valuable tool in research aimed at understanding lipid metabolism and related disorders. -
Endogenous Metabolite
(S,S)-Dehydroemetine is an endogenous metabolite with antispasmodic properties, primarily targeting smooth muscle contraction. This compound exhibits inhibitory activity, making it a valuable reagent for research into disorders associated with aberrant smooth muscle activity, such as gastrointestinal and respiratory conditions. Its potential applications extend to the study of therapeutic strategies aimed at modulating smooth muscle function. -
Endogenous Metabolite
O-Acetyl-L-serine hydrochloride functions as an endogenous metabolite involved in various biochemical pathways. This compound plays a role in the synthesis of cysteine and is crucial for cellular metabolism. Its applications include research in metabolic disorders and studies related to amino acid metabolism. -
Endogenous Metabolite
1-Benzyl-3-phenylthiourea is an endogenous metabolite that acts as a sensor material for nerve agents and their simulants. This compound exhibits biosensor activity, enhancing the sensitivity and detection capabilities of various sensor systems. Its reactive characteristics closely mimic those of nerve agents, making it a reliable candidate for improving detection methods in chemical research applications. -
Endogenous Metabolite
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate is an endogenous metabolite known for its role in cellular signaling pathways. It serves as a lipid mediator, influencing various biological processes such as cell proliferation and differentiation. This compound has applications in research related to metabolism, cell biology, and the study of lipid-related diseases. -
Endogenous Metabolite
Sodium creatine phosphate dibasic tetrahydrate is an endogenous metabolite that serves as a key substrate for creatine kinase. This compound plays a critical role in the resynthesis of ATP during skeletal muscle contraction, facilitating energy production in muscle tissues. It is widely used in biochemical research to study muscle metabolism and energy dynamics. -
Fungal Metabolite
D-Iditol is a fungal metabolite characterized as a sugar alcohol that accumulates in cases of galactokinase deficiency. It is of interest for its potential antitumor activity, making it a valuable compound for research related to cancer biology and metabolic disorders. Studies may explore its effects on cellular processes and its potential therapeutic applications. -
Endogenous Metabolite
Potassium 2-hydroxy-2-methylsuccinate is an endogenous metabolite that plays a critical role in metabolic pathways. It is known for its involvement in energy production and regulation of physiological processes. This compound can be utilized in research applications focusing on metabolic studies, biomarker identification, and the investigation of metabolic disorders. -
Endogenous Metabolite
Oxalic acid diammonium monohydrate is a strong dicarboxylic acid that serves as an endogenous metabolite, playing a significant role in various biological processes. Its applications include use as an analytical reagent and a general reducing agent in chemical research. This compound is particularly valuable in studies related to plant metabolism and the identification of organic compounds in biological samples. -
Endogenous Metabolite
L-(−)-Glyceraldehyde is an endogenous metabolite that plays a pivotal role as an intermediate in carbohydrate metabolism. It is involved in various biochemical pathways, contributing to glycolysis and other metabolic processes. This compound is essential for studying metabolic regulation and enzyme activity in research applications focused on energy metabolism and carbohydrate biosynthesis. -
Endogenous Metabolite
Indole-3-butyric acid potassium acts as a plant growth auxin, promoting the rooting of herbs and woody ornamental plants. This compound enhances fruit set and is a key precursor to indole-3-acetic acid (IAA) via peroxisomal β-oxidation. Its applications extend to agricultural research and horticultural studies, emphasizing its importance in plant developmental processes. -
Endogenous Metabolite
3-Aminocoumarin, an endogenous metabolite, functions as a key intermediate in the synthesis of metal complexes. This compound exhibits significant biological activity and is utilized in various research applications, including studies on coordination chemistry and the development of fluorescent probes. Its versatile structure facilitates exploration in medicinal chemistry and materials science. -
Endogenous Metabolite
Rac-1-Linoleoyl-3-linolenoyl-propanetriol is an endogenous metabolite that acts as a diacylglycerol. This compound features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position, and is typically derived from olive oil through lipase-catalyzed glycerolysis using immobilized lipase B from C. antarctica. It is of significant interest in research related to lipid metabolism, signaling pathways, and potential health benefits associated with dietary fatty acids. -
Endogenous Metabolite
5-Aminoimidazole ribonucleotide (AIR) is an endogenous metabolite that serves as a key intermediate in purine biosynthesis. AIR undergoes further enzymatic modifications, ultimately leading to the production of inosine monophosphate (IMP), a precursor for the purine bases adenine and guanine. This compound is essential for research in metabolic pathways, nucleotide biosynthesis, and cellular energy regulation.
