Oxidative Phosphorylation (OXPHOS)

IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS).

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Gboxin inhibits the activity of F0F1 ATP synthase. Antitumour activity.

Atovaquone is an anti-protozoal mitochondrial electron transport inhibitor.

Imeglimin is an oxidative phosphorylation blocker that acts to inhibit hepatic gluconeogenesis, increase muscle glucose uptake, and restore normal insulin secretion.

Imeglimin is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic ??-cells to uniquely target the key defects of type 2 diabetes.

FCCP is an ionophore that is a mobile ion carrier. It is a potent uncoupler of oxidative phosphorylation in mitochondria that disrupts ATP synthesis by transporting protons across cell membranes.

Oxyclozanide is a salicylanilide anthelmintic that is a proton ionophore which uncouples oxidative phosphorylation of the target organism.

Acetomenaphthone is synthetic vitamin K which is also known as vitmin K4

Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.

IACS-010759 Hydrochloride is a potent inhibitor of complex I of oxidative phosphorylation (OXPHOS).

VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS).