Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
1,2-Dioctanoyl-3-decanoyl-rac-glycerol is a triglyceride that serves as an endogenous metabolite identified in microalgae biomass through ion mobility-mass spectrometry. This compound is essential for characterizing microalgae biomass, enabling researchers to investigate its distribution across various microalgae species and its interactions with other metabolites. Its applications extend to the field of biofuel production, making it a valuable tool for understanding lipid composition and optimizing biomass yields. -
Endogenous Metabolite
Rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate is an endogenous metabolite that serves as a key intermediate in various metabolic processes. This compound exhibits significant biological activity, influencing metabolic pathways associated with energy production and cellular signaling. It is utilized in research applications focused on metabolic disorders and the biochemical mechanisms underlying cellular metabolism. -
Endogenous Metabolites
Taurodehydrocholic acid is a bile acid that acts as an endogenous metabolite, primarily influencing cholesterol metabolism. It is known to significantly enhance the expression of Abcg5 while reducing the expression of Abca8, thereby regulating biliary cholesterol secretion. This compound serves as a valuable tool for investigating mechanisms underlying cholesterol homeostasis and related metabolic disorders. -
Endogenous Metabolite
1,2-Dioleoyl-3-linoleoyl-rac-glycerol (OOL) is a triacylglycerol targeting endogenous lipid metabolism. It comprises oleic acid at the sn-1 and sn-2 positions and linoleic acid at the sn-3 position. OOL is present in various seed and vegetable oils, such as pumpkin seed, olive, and sesame oils, making it relevant for studies related to lipid profiles and metabolic pathways in nutritional and physiological research. -
Endogenous Metabolite
[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite that primarily targets mitochondrial metabolism. This compound plays a critical role in the regulation of fatty acid oxidation and energy production. It is utilized in research applications investigating metabolic disorders, mitochondrial dysfunction, and the mechanisms of energy homeostasis. -
Nrf2 Pathway Activator
Pyrraline is an Nrf2 pathway activator that enhances antioxidant defenses and mitigates inflammation. It promotes the upregulation of antioxidant enzymes, including NAD(P)H dehydrogenase (NQO1) and heme oxygenase-1 (HO-1), through the activation of the antioxidant response element (ARE), while also inhibiting NFκB-mediated inflammatory pathways. This compound holds significant potential for investigations into metabolic disorders, such as diabetic nephropathy, as well as various cancer research applications. -
Endogenous Metabolite
7β,25-Dihydroxycholesterol is an endogenous metabolite that functions as a chemoattractant for immune cells expressing EBI2. This compound plays a significant role in modulating immune responses and has implications in studies related to inflammation and autoimmune diseases. Its ability to guide immune cell migration makes it a valuable tool for research exploring immune system dynamics and therapeutic interventions. -
Endogenous Metabolite
(±)-Equol 4'-sulfate sodium is a sodium salt of the endogenous metabolite derived from the isoflavonoid phytoestrogen (±)-Equol. It plays a crucial role in estrogenic activity and serves as a significant biomarker in hormone-related research. This compound is of interest for studies investigating the effects of phytoestrogens on health, as well as their potential implications in various biological pathways. -
Endogenous Metabolite
Quercetin 5-O-β-D-glucopyranoside is a flavonoid that acts as an endogenous metabolite. It plays a significant role in the metabolic processes of insects, as evidenced by its presence in the cocoon shell of Bombyx mori. This compound exhibits antioxidant properties and is utilized in various research applications, including studies on insect metabolism and the exploration of flavonoid biosynthesis in plants. -
Endogenous Metabolite
Urobilin hydrochloride is an endogenous metabolite derived from the breakdown of hemoglobin. This compound is primarily excreted through urine and feces in various mammals, serving as an important biomarker for assessing human waste pollution. Its detection and quantification can be utilized in environmental monitoring and studies related to metabolic disorders. -
Endogenous Metabolite
L-(+)-Fructose, 95% is the L-isomer of D-Fructose, functioning as an endogenous metabolite with a crucial role in glycolysis and gluconeogenesis. This reagent is essential for studies related to photosynthesis and carbohydrate storage in plant biology, offering insights into metabolic pathways. Additionally, L-(+)-Fructose, 95% can be utilized to explore the activity of fructokinase and other enzymes involved in fructose metabolism, aiding in the understanding of carbohydrate dynamics in various biological systems. -
Endogenous Metabolite
Tetrachlorvinphos is an organophosphorus compound that primarily acts as a cholinesterase inhibitor. This metabolite is commonly utilized in agricultural settings for pest control due to its effectiveness against a variety of insects. With low toxicity to mammals, tetrachlorvinphos serves as a useful tool for studying pesticide interactions and their effects on non-target organisms. -
Endogenous Metabolite
(S)-3-Hydroxypropane-1,2-diyl dioctanoate is an endogenous metabolite and a cell-permeable analog of the PKC-activating second messenger diacylglycerol (DAG). It plays a crucial role in cellular signaling processes and is known to induce the acrosome reaction in human sperm. This compound is valuable for studying mechanisms of sperm activation and related reproductive biology research. -
Endogenous Metabolite
C17 Sphingomyelin (d18:1/17:0) is a synthetic derivative of sphingomyelin, primarily functioning as an internal standard for the quantification of sphingomyelin levels in biological samples. It serves as a valuable tool in lipidomics research, facilitating the analysis of sphingolipid metabolism and its implications in various biological processes. This compound is essential for precisely measuring sphingomyelin concentrations and understanding its role in cellular function and disease mechanisms. -
Endogenous Metabolite
Isocolumbin is a diterpenoid metabolite derived from Jateorhiza palmate Miers, commonly known as Colombo root. It exhibits various biological activities, including anti-inflammatory and antioxidant effects. Isocolumbin serves as a valuable tool for research applications in pharmacology and natural product studies, potentially aiding in the discovery of therapeutic agents. -
Endogenous Metabolite
2-Keto-3-deoxy-6-phosphogluconate is an endogenous metabolite that plays a crucial role as an intermediate in the Entner-Doudoroff pathway. This compound is significant for understanding the degradation processes of sugar acids and sugar polymers in both human and plant pathogens. Its formation is catalyzed by KDPG aldolase, making it vital for metabolic research and studies focused on microbial metabolism. -
Endogenous Metabolite
L-2-Phosphoglyceric acid is an endogenous metabolite that plays a crucial role in cellular metabolism. It serves as an intermediate in the phosphoglycerate pathway, influencing biochemical reactions related to glycolysis and gluconeogenesis. This compound is of interest in research applications focusing on metabolic studies and investigations into energy production and regulation within cells. -
Endogenous Metabolite
CE(16:1(9Z)), also known as cholesteryl palmitoleate, is a cholesterol ester that serves as an endogenous metabolite. It is notably elevated in the plasma of ApoE-/- mice subjected to cigarette smoke exposure and in pediatric patients with biliary atresia. This compound is commonly used as a reference standard for the identification and study of cholesterol esters in human meibomian gland secretions, contributing to investigations in lipid metabolism and related disorders. -
Endogenous Metabolite
Ganglioside GD1b Disodium Salt (Bovine Brain) is an acidic glycosphingolipid that acts as an endogenous metabolite and is characterized by two sialic acid residues connected to an internal galactose unit. This compound is known to facilitate the formation of lipid microdomains through its interaction with cholesterol, thereby influencing intracellular and intercellular signaling. Elevated levels of Ganglioside GD1b have been associated with aging and higher grades of pilocytic astrocytoma, as well as being present in various gliomas, including glioblastomas, primitive neuroectodermal tumors, and anaplastic astrocytomas, highlighting its potential relevance in cancer research. -
Endogenous Metabolite
Dehydrochenodeoxycholic acid is an endogenous metabolite and a ketone bile acid that plays a role in various physiological processes. Its primary mechanism involves the modulation of bile acid synthesis and metabolism, influencing lipid digestion and absorption. This compound is used in research applications focused on gastrointestinal health, lipid metabolism, and potential therapeutic implications related to metabolic disorders and liver function. -
Endogenous Metabolite
UCM-05194 is a selective agonist of the LPA1 receptor, primarily targeting neuropathic pain pathways. This compound exhibits potent activity by triggering LPA1-mediated cellular effects, leading to receptor internalization and functional inactivation in primary sensory neurons. UCM-05194 effectively reduces pain perception in in vivo models, making it a valuable tool for investigating mechanisms underlying progressive systemic diseases and potential therapeutic applications in pain management. -
Endogenous Metabolite
2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride functioning as an endogenous metabolite. This compound plays a critical role in lipid metabolism and cellular signaling pathways. Its biological activity makes it valuable for research applications related to metabolic disorders and the study of lipid profiles in various physiological and pathological states. -
Endogenous Metabolite
Bisphenol M is an endogenous metabolite recognized for its antioxidant properties. It is utilized in various industrial applications, particularly in the production of plastics and resins, where it serves as a stabilizer and preservative. Additionally, Bisphenol M is employed in certain food packaging materials to enhance product durability and safety, making it relevant for research in material science and food safety studies. -
Endogenous Metabolite
Pantoic acid is an endogenous metabolite involved in the biosynthesis of D-pantothenic acid, a crucial component of coenzyme A. This compound plays a significant role in various metabolic pathways, including fatty acid synthesis and energy metabolism. Pantoic acid is useful for research focused on metabolic processes and the regulation of coenzyme A levels in biological systems. -
Endogenous metabolites
Indole-3-lactate-O-β-D-glucopyranoside is an endogenous metabolite that functions as a plant growth regulator. It plays a critical role in mediating plant growth and development through hormone signaling pathways. This compound is useful in research applications focused on plant biology, including studies on growth regulation and metabolic profiling. -
Endogenous Metabolite
NCX 1000 is a liver-specific nitric oxide (NO) donor compound derived from ursodeoxycholic acid (UDCA). This endogenous metabolite facilitates the release of nitric oxide, which plays a crucial role in various physiological processes, particularly in liver function. NCX 1000 is primarily used in research applications focusing on hepatic biology, NO signaling pathways, and the investigation of liver-related diseases. -
Endogenous Metabolite
(±)-γ-Tocopherol is an endogenous metabolite that plays a critical role in various biological processes. It exhibits potent antioxidant properties and has been shown to influence cell signaling pathways that may be relevant in the context of cancer research. This compound is particularly useful for investigating its potential role in the pathogenesis of prostate and endometrial cancers. -
Endogenous Metabolite
aPKC-IN-2 is a selective inhibitor of atypical protein kinase C (aPKC), targeting its activity to modulate cellular signaling pathways. This compound effectively reduces vascular endothelial permeability in both in vitro and in vivo models, demonstrating significant actions against vascular endothelial growth factor (VEGF) and tumor necrosis factor (TNF). aPKC-IN-2 interferes with NFκB-mediated gene transcription, highlighting its role in regulating inflammatory responses. The EC50 value of aPKC-IN-2 is in the low nanomolar range, laying the groundwork for advancing small molecule aPKC inhibitors in therapeutic research. -
Endogenous Metabolite
3β,7α-Dihydroxycholest-5-enoic acid is an endogenous metabolite involved in cholesterol metabolism. This compound plays a role in bile acid synthesis and may influence lipid homeostasis. It is useful in research applications focused on lipid biology, metabolic disorders, and cholesterol-related diseases. -
Endogenous Metabolite
MAGL-IN-3 is a selective inhibitor of monoacylglycerol lipase (MAGL) with an IC50 of 34.1 nM. This compound effectively reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release in Neuro2a cells at a concentration of 1 μM. Additionally, administration of MAGL-IN-3 at a dosage of 10 mg/kg significantly elevates levels of 2-arachidonoyl glycerol in mouse brain, making it a valuable tool for studying endocannabinoid signaling and neurobiological processes. -
Endogenous Metabolite
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol that features linoleic acid side chains at the sn-1 and sn-2 positions, targeting various metabolic pathways. It plays a significant role as a component of phosphatidic acid in rat liver mitochondria and spinach chloroplast membranes. Additionally, this compound is identified as a potential biomarker for predicting preeclampsia in early pregnancy, making it relevant for studies on pregnancy-related conditions and lipid metabolism. -
Endogenous Metabolite
Acetonitrile-15N is a stable isotope-labeled compound primarily utilized as an endogenous metabolite in metabolic research. With applications in biolabeling experiments, it facilitates the tracking of metabolic pathways and elucidation of chemical reaction mechanisms within various organisms. Additionally, Acetonitrile-15N is instrumental in environmental science, aiding in the study of pollutant migration and transformation processes. -
Endogenous Metabolite
Biotin sodium, an endogenous metabolite, functions as a critical coenzyme for five carboxylases in humans. It plays a vital role in various metabolic processes, including fatty acid synthesis, isoleucine and valine metabolism, and gluconeogenesis. This water-soluble B vitamin is essential for cell growth and the metabolism of fats and amino acids, making it valuable in biochemical research and applications related to metabolism and nutrition. -
Endogenous Metabolite
Methyl cyclohexanecarboxylate acts as an endogenous metabolite in various biological systems. This compound plays a role in metabolic pathways and can be utilized in research focusing on metabolomics and biochemical analysis. Its study may provide insights into metabolic regulation and physiological functions. -
Endogenous Metabolite
Jalapinolic acid (11-Hydroxyhexadecanoic acid; 11-Hydroxypalmitic acid) is an endogenous metabolite with potential roles in lipid metabolism and cellular signaling. This hydroxyhexadecanoic acid has been shown to influence various biological processes, making it valuable for research into metabolic disorders and the study of fatty acid derivatives. Its unique biochemical properties facilitate investigations into its effects on cellular functions and metabolic pathways. -
Endogenous Metabolite
Estriol 16α-(β-D-glucuronide) is an endogenous metabolite primarily involved in estrogen metabolism and is prevalent in urine. It serves as a valuable biomarker in pregnancy-related research, aiding in the assessment of fetal development and maternal health. This compound is essential for studies investigating hormonal changes during gestation and may provide insights into various pregnancy complications. -
Endogenous Metabolite
(±)7(8)-EpDPA is an epoxide derivative of docosahexaenoic acid (DHA) formed through CYP450-mediated metabolism. This compound serves as an endogenous metabolite and is involved in various cellular processes, including inflammation and cellular signaling. It is utilized in research to study the biochemical pathways of omega-3 fatty acids and their effects on physiological functions. -
Transglucosidase
Sucrose phosphorylase is a bacterial transglucosidase that facilitates the conversion of sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose. This enzyme can also hydrolyze the glucosylated product into α-D-glucose or transfer the glucosyl moiety to hydroxyl groups of acceptors, leading to the formation of novel α-D-glucoside compounds. Sucrose phosphorylase exhibits specific enzymatic activity, making it valuable for applications in carbohydrate synthesis and bioconversion research. -
Endogenous Metabolite
GSK 1842799 hydrochloride is a selective agonist for the S1P1 receptor, exhibiting potent agonistic activity with notable selectivity over the S1P3 receptor. This compound demonstrates favorable oral bioavailability and is rapidly converted to its active phosphorylated form. In vivo studies reveal that GSK 1842799 hydrochloride significantly reduces blood lymphocyte counts after oral administration. Additionally, it has shown efficacy comparable to FTY720 in the mouse EAE model of multiple sclerosis, making it a valuable tool for research in immunology and neurodegenerative diseases. -
Endogenous Metabolite
Fenamidone is a potent agricultural fungicide that primarily targets mitochondrial respiratory complex II. It exhibits high biological activity against a range of plant pathogens, leading to effective disease control in various crops. Fenamidone is valuable in research applications focused on plant physiology, fungicide resistance mechanisms, and metabolic pathways in fungi. -
Endogenous Metabolite
SNAP-7941 is a selective antagonist of the melanin concentrating hormone receptor MCH1, exhibiting anxiolytic, antidepressant, and appetite-suppressant properties. In preliminary animal studies, SNAP-7941 demonstrated significant biological activity and the ability to inhibit MCH-induced drinking behavior, highlighting its potential for research in neuropharmacology and metabolic disorders. This compound serves as a valuable tool for investigating the role of MCH1 in various physiological processes. -
Endogenous Metabolite
1-Deoxysphingosine is an endogenous metabolite that acts as a deoxy-sphingoid base, characterized by a (4E) double bond in its structure. This compound is notably elevated in the lymphoblasts of individuals with hereditary sensory neuropathy type 1 (HSAN1), highlighting its potential relevance in neuropathic disorders. It is produced through the catabolism of 1-deoxyceramide, catalyzed by the ceramidase enzyme, making it a valuable target for research in sphingolipid metabolism and related cellular processes. -
Endogenous Metabolite
16-Ketoestradiol is an endogenous metabolite of estrone, a naturally occurring estrogen. It plays a critical role in the regulation of estrogenic activity within the body, influencing various physiological processes. This compound is important for research applications related to hormonal studies and the exploration of estrogen-related disorders. -
Endogenous Metabolite
Ocaphane is an endogenous metabolite with demonstrated potential as an antitumor agent. It exhibits significant cytotoxic activity against a variety of animal tumor models, making it a valuable tool for cancer research. This compound can be utilized to investigate tumor biology and evaluate therapeutic strategies in preclinical studies. -
Endogenous Metabolite
Kahalalide A is an anti-mycobacterial compound derived from the marine mollusk Elysia rufescens, targeting various microbial pathogens. This endogenous metabolite exhibits significant antimicrobial activity, making it a valuable candidate for research in natural product pharmacology. Its unique structure and bioactivity have garnered interest for potential therapeutic applications in combating infectious diseases. -
Endogenous Metabolite
p60 (217–225) is a subdominant epitope derived from Listeria monocytogenes, recognized by H-2Kd MHC class I molecules. This peptide plays a crucial role in the immune response to Listeria infection, facilitating T cell recognition and activation. p60 (217–225) is essential for studying antigen presentation and T cell immunity in infectious disease research and vaccine development. -
Endogenous Metabolite
ISQ-1 hydrochloride is an isoquinolinone compound that functions as an inhibitor of the IKur potassium channel. It demonstrates potential to influence cardiac electrophysiology by modulating arrhythmic activity in atrial tissues. This reagent is primarily utilized in research focused on cardiac rhythm disorders and electrophysiological studies of heart functions. -
Endogenous Metabolite
N4-Acetylsulfamerazine is a sulfonamide derivative that primarily targets endogenous metabolites. It exhibits antibiotic activity, specifically inhibiting bacterial growth through interference with folic acid synthesis. This compound is valuable for studying sulfonamide pharmacology and understanding metabolic pathways in microbial resistance. Its applications extend to research in infectious diseases and pharmacokinetics. -
Herbicide
Florasulam, a selective post-emergent herbicide, targets acetolactate synthase (ALS) in plants. By inhibiting ALS, which is essential for the biosynthesis of branched-chain amino acids, Florasulam disrupts critical metabolic processes associated with plant growth and cell division. This efficacy makes it valuable for agricultural research and the development of effective weed management strategies. -
Endogenous Metabolite
Altertoxin II is an endogenous metabolite derived from Alternaria alternata, known for its mutagenic properties. It exhibits mutagenicity in various strains of Salmonella typhimurium, including TA98, TA100, and TA1537, both in the presence and absence of metabolic activation. This compound serves as a valuable tool for investigating the mechanisms of mutagenesis associated with mycotoxins, contributing to understanding their impact on genetic material.
