Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite,Cancer Inhibitor
Protoporphyrin IX (disodium) is a key metabolite in the heme biosynthetic pathway, functioning primarily as a radiation sensitizer. It enhances the generation of reactive oxygen species (ROS) even under hypoxic conditions, thereby inducing DNA damage. This compound also serves as a photosensitizer, undergoing photodegradation when exposed to light. Notably, Protoporphyrin IX (disodium) accumulates in tumor cells following administration of 5-aminolevulinic acid (5-ALA) and demonstrates selective efficacy against basal cell carcinoma when activated at a wavelength of 405 nm. Its properties make it a valuable candidate for research into sonodynamic and photodynamic therapies for various cancers, including bladder cancer. -
Endogenous Metabolite
(±)-Coriolic acid is an endogenous metabolite formed from the non-enzymatic oxidation of linoleic acid, classified as a racemic monohydroxy fatty acid. This compound serves as a significant hydroxy fatty acid in psoriatic skin scales, where it is found at a mean concentration of 17 ng/mg. Research applications include the study of lipid metabolism and skin pathology, particularly in relation to inflammatory skin disorders. -
Endogenous Metabolite
N-Palmitoyl Taurine is an endogenous metabolite identified as a prominent acyl amino acid in lipidomic studies of rat brain tissue. This compound plays a role in modulating endocannabinoid signaling pathways, which are critical for various neurophysiological processes. Research applications of N-Palmitoyl Taurine include investigating its potential neuroprotective effects and implications in neurodegenerative disorders. Further studies are ongoing to elucidate its biological functions and mechanisms of action. -
Endogenous Metabolite
15(S)-HETE is an endogenous metabolite that serves as a biomarker for Zellweger Syndrome. This compound is primarily involved in lipid metabolism and signaling pathways related to cellular function and inflammation. It is valuable for researchers investigating the biochemical and physiological processes affected in Zellweger Syndrome and other related disorders. -
Endogenous Metabolite
Phytic acid potassium is an endogenous metabolite known for its role as a chelator of metal ions. It has been shown to exhibit antioxidant properties and can influence cellular signaling pathways. This compound is utilized in biochemical research to study its effects on mineral bioavailability and its potential role in various physiological processes. -
Endogenous Metabolite
Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a key structural glycoprotein that plays an essential role in tissue architecture and cellular interactions. It serves as a scaffold by interacting with type IV collagen, facilitating cell adhesion through integrin receptors, and promoting neurite outgrowth. Its various functional domains are critical for collagen binding and heparin interaction, making it a vital component in studies related to cell behavior, tissue engineering, and developmental biology. -
Endogenous Metabolite
NSC 13138 is an endogenous metabolite that plays a crucial role in various metabolic pathways. Its biological activity is linked to influencing intracellular signaling processes, making it relevant for research in metabolic regulation and homeostasis. This compound serves as a valuable tool for studying metabolic changes in disease models and understanding its implications in cellular functions. -
Endogenous Metabolite
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an essential endogenous metabolite involved in nucleic acid metabolism. It serves as a precursor for DNA synthesis and plays a crucial role in cellular processes including DNA repair and replication. dCMP disodium is utilized in biochemical research to study DNA-related activities and pathways, enhancing the understanding of cellular functions and genetic regulation. -
Endogenous Metabolite
D-Xylulose is an endogenous metabolite that plays a key role in carbohydrate metabolism. It serves as a precursor for the pentitol D-arabitol, contributing to various metabolic pathways. D-Xylulose is valuable for research applications focused on metabolic disorders and the physiological roles of sugar alcohols. -
Endogenous Metabolite
1-Methylguanidine monohydrochloride is a key endogenous metabolite involved in various biological processes. This compound has been linked to the regulation of nitrogen metabolism and is studied for its role in the understanding of metabolic disorders. Its relevance in research includes investigating the effects of methylated guanidines in physiological and pathological conditions. -
Endogenous Metabolite
D-Lysine is an endogenous metabolite that serves as an analog of luteinizing hormone-releasing hormone and acts as a carrier agent in polylysine formulations. This compound is utilized in enhancing renal uptake during scintigraphy and peptide receptor radionuclide therapy (PRRT) with minimal toxicity. D-Lysine maintains the natural balance of amino acid metabolism, making it a valuable component in various biochemical research applications. -
Endogenous Metabolite
D-Glucosamic acid is an endogenous metabolite involved in various biochemical pathways. It plays a crucial role in the metabolism of carbohydrates and amino acids. This compound is commonly used in research applications focused on metabolic studies and understanding cellular processes related to glycosylation and other modifications. -
Endogenous Metabolite
Pentane-1,5-diamine dihydrochloride is an endogenous metabolite that serves as a key substrate in various biological pathways. Its primary mechanism involves acting as a building block for polyamines, which are crucial for cellular growth, differentiation, and regulation of gene expression. This compound is commonly used in research applications focusing on metabolic processes and the study of polyamine biosynthesis in different biological systems. -
Endogenous Metabolite
Methyl p-tert-butylphenylacetate is an endogenous metabolite that plays a role in various biological processes. This compound is often utilized in research applications focusing on metabolic pathways and the study of metabolite effects on cellular functions. Its characterization aids in understanding physiological responses and disease mechanisms associated with endogenous compounds. -
Endogenous Metabolite
Phenylpropiolic acid is an endogenous metabolite and a versatile click chemistry reagent characterized by its alkyne group. This compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc), making it a valuable tool in bioconjugation and chemical biology applications. It is widely used in the synthesis of complex biomolecules and in the study of cellular processes involving azide-labeled targets. -
Endogenous Metabolite
Bamethan hemisulfate is an endogenous metabolite that functions as a vasodilator by enhancing blood flow and decreasing vascular resistance. It plays a critical role in the treatment of cardiovascular diseases by improving oxygen delivery to tissues. Additionally, Bamethan hemisulfate is effective in managing hypertension due to its relaxing effects on blood vessels, making it a valuable compound for cardiovascular research applications. -
Endogenous Metabolite
5(S)-HETE is an endogenous metabolite that plays a significant role in inflammatory processes. It is involved in the modulation of immune responses and is relevant in the study of various conditions, including rheumatoid arthritis, rhinitis, and asthma. This compound serves as a valuable tool for understanding the biochemical pathways associated with these inflammatory diseases. -
Endogenous Metabolite
5-Hydroxymethyluracil is an endogenous metabolite derived from oxidative DNA damage. It serves as a potential epigenetic marker, influencing transcriptional activity by modulating the function of bacterial RNA polymerase. This compound is valuable for research into mechanisms of DNA repair, epigenetic regulation, and transcriptional dynamics. -
Endogenous Metabolite
D-Glyceric acid sodium is the sodium salt of D-Glyceric acid, an endogenous metabolite found in human urine. This compound plays a significant role in metabolic pathways and serves as a valuable research tool for investigating conditions such as primary hyperoxaluria type I and glutaric acidemia type II. Its application extends to studying metabolic disorders and understanding related biochemical processes. -
Endogenous Metabolite
3-Phenylbutyric acid is an endogenous metabolite known for its role in various metabolic pathways. This compound exhibits potential as a selective agent for isolating Rhodococcus rhodochrous PB1, facilitating research into microbial biotechnology and environmental sciences. Its unique structure enables exploration in studies related to phenylpropanoid metabolism and microbial interactions in compost environments. -
Endogenous Metabolite
N-Lactylleucine is an endogenous metabolite associated with metabolic processes in the human body. It plays a notable role in identifying patients with intermediate maple syrup urine disease, a disorder impacting amino acid metabolism. This compound is valuable for research applications focused on metabolic disorders and the biochemical pathways related to amino acid regulation. -
Endogenous Metabolite
N-Lactylvaline is an endogenous metabolite primarily associated with metabolic pathways related to branched-chain amino acids. It has been identified in patients with intermediate maple syrup urine disease, serving as a potential biomarker for diagnosing metabolic disorders. This compound can be utilized in research applications aimed at understanding metabolic derangements and developing therapeutic interventions. -
Endogenous Metabolite
Glutathione sulfonate (S-Sulfoglutathione) is a competitive inhibitor of glutathione S-transferase, targeting its substrate binding site, which significantly impacts the enzyme's catalytic activity. This endogenous metabolite is known for its multifunctional properties, including the inhibition of angiogenesis and tumor growth. It plays a crucial role in the detoxification of various exogenous and endogenous compounds and is valuable for research applications focusing on cancer biology and metabolic processes. -
Endogenous Metabolite
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite that serves as a critical component of cell membranes. This phospholipid plays a significant role in modulating cellular signaling pathways and contributing to membrane fluidity. It is utilized in research applications involving lipid metabolism, membrane biology, and the study of lipid-mediated signaling processes. -
Endogenous Metabolite
3-Hydroxypropionic acid sodium is an endogenous metabolite involved in various biochemical pathways. It serves as a versatile building block in chemical synthesis, particularly in the production of polymers and other complex molecules. This compound is crucial for research applications focused on metabolic pathways and synthetic biology, enhancing the understanding of metabolic processes and enabling the development of innovative materials. -
Endogenous Metabolite
3-Oxochenodeoxycholic acid is an endogenous metabolite that plays a role in several physiological processes. As a potential biomarker, it may assist in the diagnosis of certain conditions, including COVID-19. This compound is primarily utilized in research focused on metabolic pathways and disease state characterization. -
Endogenous Metabolite
Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that serves as an endogenous metabolite. It acts as a precursor in the synthesis of guanosine monophosphate (GMP) and adenosine monophosphate (AMP), playing a pivotal role in nucleotide metabolism. This compound is utilized in various research applications, including studies of taste perception and metabolism in cellular processes. -
Endogenous Metabolite
PAz-PC (Azelaoyl Phosphatidylcholine) is an endogenous metabolite derived from oxidized low-density lipoprotein (oxLDL) particles. It contains a unique oxidized short-chain fatty acid remnant at the sn-2 position, contributing to its cytotoxic and pro-atherogenic properties. PAz-PC is a critical structural component in oxLDL and is valuable in research exploring lipid metabolism, atherosclerosis, and cardiovascular disease mechanisms. -
Endogenous Metabolite
5-Hydroxymethylcytosine (5hmC) is an oxidized derivative of 5-methylcytosine found within mammalian DNA. Generated through an enzymatic process involving the Ten-eleven translocation (TET) enzymes TET1, TET2, and TET3, 5hmC serves as an important marker for investigating the dynamic processes of DNA demethylation and gene transcription. Its presence is particularly significant in the study of conditions such as non-small cell lung cancer, neurodegenerative diseases like Alzheimer’s and Parkinson’s, and various hematological malignancies, including acute myeloid leukemia and myelodysplastic syndromes. -
Endogenous Metabolite
1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC is an endogenous metabolite and a plasmalogen, featuring 1(Z)-octadecenoic acid at the sn-1 position and arachidonic acid at the sn-2 position. It exhibits significant singlet oxygen scavenging activity in cell-free assays, making it valuable for research into oxidative stress and related biological processes. This compound has potential applications in studies focusing on lipid metabolism, cell signaling, and neuroprotection. -
Endogenous Metabolite
2,8-Dihydroxyadenine is an endogenous metabolite with a crucial role in the diagnosis of adenine phosphoribosyltransferase (APRT) deficiency. Its accumulation can lead to the formation of urinary crystals and kidney stones, making it significant in renal pathology studies. This compound is valuable for investigating metabolic disorders and understanding crystal-induced nephropathy. -
Endogenous Metabolite
2-Methylbenzaldehyde is a naturally occurring metabolite that functions primarily as a signaling molecule in various biochemical pathways. It is involved in the regulation of metabolic processes and plays a role in the synthesis of aromatic compounds. This compound is useful in research applications related to metabolic profiling, enzymatic studies, and the investigation of cellular signaling mechanisms. -
Endogenous Metabolite
(S)-Nornicotine is an endogenous metabolite of nicotine with implications in nicotine addiction and neurobiological research. It serves as a valuable tool for studying the pharmacological effects of nicotine and its derivative compounds. Its role in receptor modulation and potential influence on neurotransmitter systems makes it relevant for investigations into smoking cessation and substance use disorders. -
Endogenous Metabolite
(E)-Oct-2-enoic acid is an endogenous metabolite that plays a role in various biological processes. This compound is involved in metabolic pathways and can serve as a valuable tool in research focused on metabolic regulation and physiological functions. Its unique properties make it suitable for studies investigating the impact of metabolites on cellular signaling and related activities. -
Endogenous Metabolite
Fructosyl-lysine dihydrochloride is an amadori glycation product that arises from the reaction between glucose and lysine via the Maillard reaction. This compound serves as a precursor to glucosepane, a significant lysine–arginine protein cross-link implicated in diabetic pathology. Its measurement can be valuable for assessing glycemic control and may serve as a biomarker for the early detection of diabetes. Research applications include studying glycation processes and their impact on protein function and structure in various biological systems. -
Endogenous Metabolite
3-Methylindolin-2-one is an endogenous metabolite known for its involvement in various biochemical pathways. This compound plays a critical role in biological processes and is utilized in research focused on metabolic studies and the exploration of cellular functions. Its applications extend to studies in pharmacology and toxicology, contributing to the understanding of drug metabolism and physiological responses. -
Endogenous Metabolite
5-Methoxy-5-oxopentanoic acid is an endogenous metabolite known to play a role in various metabolic pathways. It has been implicated in regulating energy metabolism and may influence physiological processes related to metabolic disorders. This compound is suitable for research applications focused on understanding metabolic functions and the role of endogenous metabolites in biological systems. -
Endogenous Metabolite
Trans-2-butene-1,4-dicarboxylic acid is an endogenous metabolite with significant roles in various biochemical pathways. This compound is of interest for studying metabolic processes and cellular responses, particularly in the context of energy metabolism and biosynthesis. Its unique structure and biological activity make it a valuable reagent for research applications in metabolomics and related fields. -
Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid and serves as an endogenous metabolite. This compound plays a significant role in lipid metabolism and may influence various physiological processes. It is commonly used in research to study fatty acid biosynthesis, metabolic pathways, and their implications in health and disease. -
Endogenous Metabolite
3-(2,4-Dihydroxyphenyl)propanoic acid is a competitive inhibitor of tyrosinase, primarily targeting the conversion of L-Tyrosine and DL-DOPA. It exhibits potent inhibitory effects, with an IC50 of 3.02 μM and a Ki of 11.5 μM. This compound is valuable in research applications focused on melanogenesis, skin pigmentation, and the study of related metabolic pathways. -
Endogenous Metabolite
1-Palmitoyl-sn-glycerol 3-phosphate sodium salt is an endogenous metabolite that serves as a key regulator in lipid metabolism. This compound is particularly relevant in the study of non-alcoholic fatty liver disease, where it can aid in understanding lipid dysregulation and related pathological processes. Its role in cellular signaling makes it a valuable tool for research in metabolic disorders. -
Endogenous Metabolite
Inosinic acid disodiumhydrate (1:2:X) is an endogenous metabolite known to play a significant role in cellular energy transfer and nucleotide synthesis. This compound is primarily utilized as a flavor enhancer due to its umami taste profile and has applications as a dietary supplement to enhance meat quality in livestock, particularly in pigs. Its ability to influence metabolic pathways makes it a valuable reagent for research in nutrition and food science. -
Endogenous Metabolite
Imidazol-1-yl-acetic acid is an endogenous metabolite that plays a significant role in various biological processes. It is involved in the regulation of cellular signaling pathways and metabolism. This reagent is valuable for research applications focused on metabolic studies, as well as the exploration of its role in physiological and pathological conditions. -
Endogenous Metabolite
5α-Cholestan-3-one is an endogenous metabolite primarily involved in cholesterol metabolism. This compound serves as a crucial intermediate in the biosynthesis of steroid hormones and is important for investigating lipid-related metabolic pathways. Its biological activity is significant in studies related to metabolic disorders and hormonal regulation. -
Endogenous Metabolite
3-Methyl-2-buten-1-ol is an endogenous metabolite that modulates physiological processes in various biological systems. This compound exhibits potential weight reduction effects, as evidenced by studies demonstrating its efficacy in animal models. It is primarily utilized in research applications related to metabolism and may hold significance for studies on fragrance compounds due to its presence in pine trees. -
Endogenous Metabolite
19-Hydroxyandrost-4-ene-3,17-dione serves as a substrate for the enzymes Corticotropin-lipotropin and Cytochrome P450 19A1. This endogenous metabolite plays a crucial role in steroidogenesis and is valuable in studies of adrenal and gonadal function. Its utility extends to research on hormone biosynthesis and the physiological effects of androgens and estrogens. -
Endogenous Metabolite
D-Threitol functions as an endogenous metabolite and plays a critical role in cryoprotection. Its primary biological activity includes acting as an antifreeze agent in organisms such as the Alaskan beetle Upis ceramboides. This compound is of interest in studies investigating metabolic adaptations to extreme cold environments and cellular responses to stress conditions. -
Endogenous Metabolite
Ac-DL-Trp-OH is an endogenous metabolite that serves as a precursor in the biosynthesis of various tryptophan-derived compounds. This compound is utilized in studies focused on metabolic pathways and neurotransmitter synthesis, particularly in relation to serotonin and melatonin production. Its application extends to research involving tryptophan metabolism and related phenotypic effects in biological systems. -
Endogenous Metabolite
L-Cysteic acid monohydrate is an endogenous metabolite and the oxidation product of L-cystine. It serves as a substrate for glutamate decarboxylase (GADCase) and cysteine sulfinic acid decarboxylase (CADCase II), playing a crucial role in neurotransmitter synthesis. This compound is valuable for research into amino acid metabolism and neurological function. -
Endogenous Metabolite
3-Furanoic acid is an endogenous metabolite known for its anti-inflammatory properties. It and its derivatives can modulate inflammation-related signaling pathways and inhibit the proliferation of synovial fibroblasts, thereby exerting significant immunomodulatory effects. This compound is valuable for research in inflammation, autoimmune disorders, and related therapeutic developments.
