(±)-Coriolic acid

Catalog No.: A71828
Endogenous Metabolite
(±)-Coriolic acid is an endogenous metabolite formed from the non-enzymatic oxidation of linoleic acid, classified as a racemic monohydroxy fatty acid. This compound serves as a significant hydroxy fatty acid in psoriatic skin scales, where it is found at a mean concentration of 17 ng/mg. Research applications include the study of lipid metabolism and skin pathology, particularly in relation to inflammatory skin disorders.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(±)-Coriolic acid is an endogenous metabolite formed from the non-enzymatic oxidation of linoleic acid, classified as a racemic monohydroxy fatty acid. This compound serves as a significant hydroxy fatty acid in psoriatic skin scales, where it is found at a mean concentration of 17 ng/mg. Research applications include the study of lipid metabolism and skin pathology, particularly in relation to inflammatory skin disorders.
Product Information
Catalog NumA71828
FormulaC18H32O3
Molecular Weight296.44
CAS Number18104-45-5
SMILESCCCCCC(O)/C=C/C=C\CCCCCCCC(O)=O
Synonyms(±)-13-HODE
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