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Taurodehydrocholic acid

Catalog No.: A72787
Endogenous Metabolites
Taurodehydrocholic acid is a bile acid that acts as an endogenous metabolite, primarily influencing cholesterol metabolism. It is known to significantly enhance the expression of Abcg5 while reducing the expression of Abca8, thereby regulating biliary cholesterol secretion. This compound serves as a valuable tool for investigating mechanisms underlying cholesterol homeostasis and related metabolic disorders.
Taurodehydrocholic acid 517-37-3 Endogenous Metabolites
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Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTaurodehydrocholic acid is a bile acid that acts as an endogenous metabolite, primarily influencing cholesterol metabolism. It is known to significantly enhance the expression of Abcg5 while reducing the expression of Abca8, thereby regulating biliary cholesterol secretion. This compound serves as a valuable tool for investigating mechanisms underlying cholesterol homeostasis and related metabolic disorders.
Product Information
Catalog NumA72787
FormulaC26H39NO7S
Molecular Weight509.66
CAS Number517-37-3
SMILESO=C1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)(C(C[C@]2([H])[C@@]4([C@](CC(CC4)=O)([H])C1)C)=O)C
SynonymsTDHC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Metabolism > Endogenous Metabolite