Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
Lacto-N-biose I (Galβ1-3GlcNAc) is an endogenous metabolite that serves as an acceptor for the α1,2-fucosyltransferase enzyme derived from Helicobacter pylori. This compound plays a critical role in glycan biosynthesis and is relevant in studies of bacterial adhesion and host-pathogen interactions. Lacto-N-biose I is valuable for research focused on glycosylation processes and microbial pathogenicity. -
Endogenous Metabolite
2,3,5-Trimethylpyrazine is an endogenous metabolite known for its role in various metabolic pathways. This compound exhibits biological activity that may influence physiological processes and is utilized in research exploring metabolic functions and pathways. Its presence in different biological samples makes it a valuable reagent for studies in metabolomics and related fields. -
Endogenous Metabolite
2-Naphthoxyacetic acid is an endogenous metabolite that acts primarily as a growth regulator in plant physiology. Its biological activity includes modulating auxin responses, which are crucial for various developmental processes in plants. This compound is commonly utilized in research applications focused on plant growth regulation and the biochemical pathways of auxin signaling. -
Endogenous Metabolite
(Z)-4-Amino-4-oxobut-2-enoic acid acts as an endogenous metabolite involved in various biochemical pathways. It is a key component in the metabolic processes of amino acids and can influence neurotransmitter synthesis. This compound is valuable for research applications focused on metabolic regulation and neurobiology, providing insights into physiological and pathological states. -
Enzyme
β-Amylase from Bacillus subtilis is a starch-degrading enzyme that hydrolyzes α-1,4-glycosidic linkages in polysaccharides. This enzyme is instrumental in various biochemical assays and research applications, particularly in studies involving carbohydrate metabolism and enzymatic activity. Its robust activity makes it suitable for use in food processing, fermentation, and the development of biofuels. -
Endogenous Metabolite
3,4-Dimethoxyphenylacetic acid is an endogenous metabolite that serves as a key building block in chemical synthesis. It exhibits important biological activity, playing a role in the synthesis of various phenolic compounds. This compound is utilized in research applications focused on metabolic pathways and the exploration of biochemical processes involving phenolic precursors. -
Endogenous Metabolite
trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite involved in fatty acid metabolism. It serves as a fatty acyl-CoA analogue, playing a key role in the transport of long-chain fatty acids into the mitochondria for β-oxidation. This compound is useful in research focused on metabolic disorders and energy metabolism, providing insights into cellular energy homeostasis and lipid metabolism. -
Endogenous Metabolite
Deoxypyridinoline is an endogenous metabolite that serves as a biomarker for bone turnover and metabolism. Its primary mechanism involves crosslinking of collagen, which is essential for maintaining bone strength and integrity. This compound is mainly utilized in research to investigate conditions related to bone disease and heart failure, providing insights into the pathophysiological mechanisms underlying these disorders. -
Phospholipase D
Phospholipase D from Streptomyces chromofuscus is an enzyme that hydrolyzes phosphodiester bonds in glycerophospholipids, producing phosphatidic acid and free choline. This enzyme plays a crucial role in various biological processes, including lipid metabolism, signal transduction, and membrane dynamics. Its activity is relevant in the study of several disease states, such as diabetes, obesity, tumorigenesis, and immune responses. Phospholipase D is widely utilized in biochemical research to investigate cellular signaling pathways and lipid-related disorders. -
Endogenous Metabolite
4-Methyloctanoic acid is an endogenous metabolite that plays a significant role in the flavor profile of sheep and goat milk, contributing to its distinctive goaty and sheepy taste. This compound is utilized in studies investigating flavor chemistry and the metabolic pathways associated with fatty acid production in dairy animals. Additionally, it may be relevant in exploring the impacts of diet on milk composition and sensory characteristics. -
Endogenous Metabolite
5-Methyltetrahydrofolic acid disodium is a vital endogenous metabolite involved in one-carbon metabolism and the transfer of methyl groups. It plays a critical role in nucleotide synthesis and amino acid metabolism, making it essential for cellular proliferation and growth. Research applications include studies on folate deficiency, methylation processes, and various metabolic disorders. -
Endogenous Metabolite
4-Hydroxy-3-methylbenzoic acid is an endogenous metabolite with pivotal roles in various biochemical pathways. Its detection in biological fluids, particularly urine, serves as a biomarker for metabolic processes in human health. This compound is utilized in research focusing on metabolism, toxicology, and disease state assessment. Its relevance in clinical studies underscores its potential in understanding metabolic disorders and monitoring physiological changes. -
Endogenous Metabolite
11-Hexadecenoic acid is a monounsaturated fatty acid that functions as an endogenous metabolite. This compound exists in two geometric isomers, 11-cis-hexadecenoic acid and 11-trans-hexadecenoic acid, which are found in ewe milk fat and are influenced by dietary lipid supplementation from sources such as linseed, sunflower, olive, or fish oils. Additionally, 11-trans-hexadecenoic acid has been identified in intramuscular fat from both male and female foals. This reagent serves as a valuable tool for research into lipid metabolism and fatty acid profiles. -
Endogenous Metabolite
C18:1 Cyclic LPA is an endogenous metabolite that serves as an analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). Its distinctive 5-membered ring structure, formed between the sn-2 hydroxy group and the sn-3 phosphate, enables C18:1 Cyclic LPA to modulate various cellular functions. Key biological activities include the inhibition of cell cycle progression, promotion of stress fiber formation, and reduction of tumor cell invasiveness and metastasis. Additionally, it influences the differentiation and survival of neuronal cells, often yielding effects that oppose those induced by LPA, despite engaging similar receptor populations. -
Endogenous Metabolite
AC-PHE-OME is a derivative of phenylalanine that serves as an endogenous metabolite. This compound is primarily utilized to study metabolic pathways involving phenylalanine and its derivatives. Its key biological activity includes functioning as a substrate in various enzymatic reactions, making it valuable for research in metabolic disorders and related biochemical processes. -
Endogenous Metabolite
(S)-OPC-51803 acts as an agonist for the vasopressin V2 receptor, primarily targeting the regulation of renal water reabsorption. This compound demonstrates significant biological activity in suppressing nocturia and urinary incontinence, exhibiting a stronger agonistic effect than its (R)-isomer. Research applications include studies on urinary function disorders and potential therapeutic interventions for conditions associated with nocturnal polyuria. -
Endogenous Metabolite
N-Lignoceroyl Taurine is an endogenous metabolite and taurine conjugate of lignoceric acid, identified through lipidomic analysis of bovine brain. This compound exhibits distinct biological activity as a substrate for fatty acid amide hydrolase (FAAH), with levels significantly elevated in FAAH knockout mice, indicating a potential role in lipid metabolism. Additionally, N-Lignoceroyl Taurine has been shown to activate transient receptor potential (TRP) calcium channels, including TRPV1 and TRPV4, highlighting its relevance in neurobiology and cellular signaling research. -
Endogenous Metabolite
5-OAHSA is an endogenous metabolite that functions as a lipid mediator. It is known to lower blood glucose levels, enhance glucose tolerance, and stimulate the secretion of glucagon-like peptide-1 (GLP-1) and insulin. 5-OAHSA is valuable for research applications focused on metabolic regulation and inflammation modulation. -
Endogenous Metabolite
Magnesium Ionophore I primarily functions as a carrier for magnesium ions, facilitating their transport across lipid membranes. This compound is essential in the development of calcium-magnesium selective electrodes, enabling precise measurement and analysis of ion concentrations in various biological samples. Its unique properties make it a valuable tool in studies involving ion transport and signaling pathways. -
Endogenous Metabolite
13,14-Dihydro-15-keto Prostaglandin F2α is an endogenous metabolite that primarily targets prostaglandin pathways. It plays a significant role in various biological processes related to pregnancy and reproductive health. This compound is instrumental in research applications focused on understanding the biochemical mechanisms of pregnancy and potential implications in related disorders. -
Insect Pheromone
(3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is an insect pheromone known for its ability to attract male South American tomato pinworms (Scrobipalpuloides absoluta). This compound plays a critical role in the communication and mating behaviors of these pests, making it valuable for research applications in pest management and ecological studies focused on agricultural systems. Its effectiveness in mimicking natural pheromones provides insights into the insect's behavioral responses and offers potential strategies for controlling tomato crop infestations. -
Endogenous Metabolite
Phosphoglycolic acid is an endogenous metabolite that plays a crucial role in linking photo-respiration with central metabolic pathways. This compound significantly affects the tissue levels of 2-phospho-glycolate, thereby influencing metabolic processes in various biological systems. Research applications include studying plant metabolism, photo-respiratory pathways, and their impact on overall plant physiological responses. -
Endogenous Metabolite
Sulforhodamine 101 DHPE is a fluorescent probe that targets endogenous metabolites through its unique conjugation of the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE with sulforhodamine 101, a red fluorescent dye exhibiting excitation/emission maxima of 586/605 nm. This reagent is well-suited for applications including imaging of solid-supported lipid bilayers, detection of protein-ligand interactions on bilayer surfaces, and monitoring the colocalization of lipid probes in liposomes using resonance energy transfer (RET) techniques. Its ability to integrate into phospholipid bilayers enhances its utility in membrane biophysics research. -
Endogenous Metabolite
6-Methyluracil, an endogenous metabolite of uracil, serves as an indicator for acetoacetyl-CoA (AACoA) accumulation in metabolic studies. This compound has demonstrated antiradiation effects in vivo, making it valuable for research in cellular protection mechanisms and metabolic regulation. Its unique properties enable applications in investigations of nucleic acid metabolism and oxidative stress responses. -
Endogenous Metabolite
AMC Arachidonoyl Amide (AMC-AA) is a synthetic substrate for fatty acid amide hydrolase (FAAH), enabling the assessment of FAAH activity. Upon hydrolysis by FAAH, AMC-AA releases aminomethyl coumarin, which exhibits fluorescence, specifically absorbing at 360 nm and emitting at 465 nm. This property makes AMC-AA an effective tool for the rapid and convenient quantification of FAAH activity in biological samples, facilitating research in lipid metabolism and neurobiology. -
Endogenous Metabolite
α-D-Xylose, an endogenous metabolite, serves as a critical component of the five-carbon fraction of biomass and a precursor of hemicellulose. This sugar participates in various enzyme-catalyzed reactions and is involved in multiple metabolic pathways. In research applications, α-D-Xylose is also utilized in the tanning and dyeing industries, as well as in formulations for diabetic food products. -
Endogenous metabolites
Clopidogrel carboxylic acid, an inactive metabolite of the antiplatelet drug Clopidogrel, primarily interacts with endogenous metabolites in human serum. This compound is significant for biochemical studies focused on metabolic pathways and drug metabolism. Its role in examining the pharmacokinetics of antiplatelet therapies makes it a valuable reagent for research in cardiovascular pharmacology. -
AMPK/SIRT3/PGC-1α Modulator
MitoPBN is an AMPK/SIRT3/PGC-1α modulator that enhances mitochondrial function by acting as a reactive oxygen species scavenger. This compound promotes mitochondrial biogenesis through increased AMPK phosphorylation, restoration of SIRT3 expression, and upregulation of PGC-1α. MitoPBN is effective in regulating glucose metabolism, as it decreases blood glucose levels by inhibiting hepatic gluconeogenesis and enhancing glucose uptake, while also improving ATP production and maintaining mitochondrial membrane potential. Additionally, it can reduce apoptosis and enhance sperm motility and membrane integrity, making it a valuable reagent for research related to diabetes and metabolic disorders. -
Endogenous Metabolite
Vitamin B12 hydrate, also known as Cyanocobalamin, acts as an endogenous metabolite crucial for neurological health and hematopoiesis. This compound supports normal brain and nervous system function, while also contributing to the formation of red blood cells. Additionally, Vitamin B12 hydrate demonstrates potential benefits in managing inflammatory diseases and offers protective effects against oxidative-stress-related conditions. Its diverse biological activities make it valuable for various research applications in neuroscience and immunology. -
Endogenous Metabolite
CE(20:3(8Z,11Z,14Z)) is a cholesterol ester that serves as an endogenous metabolite. This compound accumulates in the adrenal gland and has been observed to decrease in concentration, correlating with cognitive decline in HIV-infected individuals. Research applications include studies of cholesterol metabolism, adrenal function, and cognitive health. -
Endogenous Metabolite
L-Lysine acetate is an essential amino acid that functions as an endogenous metabolite. It is implicated in various biological processes and has been studied for its potential effects on vascular calcification and acute pancreatitis. This compound serves as a valuable tool for researchers investigating these pathological conditions and their underlying mechanisms. -
Endogenous Metabolite
γ-Glu-Phe TFA (γ-Glutamylphenylalanine TFA) is an endogenous metabolite synthesized by Bacillus amyloliquefaciens and Aspergillus oryzae. This compound is known for enhancing umami flavor profiles, making it a valuable addition in food science for improving the sensory qualities of soy sauce and chicken broth. Its applications extend to research in flavor chemistry and metabolomic studies. -
Endogenous Metabolite
Moschamine is an endogenous metabolite that functions as an inhibitor of excessive superoxide production in mitochondria. This compound has been shown to modulate oxidative stress, making it a valuable tool for research on mitochondrial dysfunction and related metabolic disorders. Its biological activity has implications for studies investigating the roles of reactive oxygen species in cellular injury and age-related diseases. -
Insect Pheromone
(7Z,9E)-Dodecadienyl acetate is a female pheromone targeting insect communication pathways. It is primarily involved in attracting male grapevine moths, playing a crucial role in mating behaviors. This compound is valuable for research applications focused on pest management and the study of insect behavior. -
Tyrosinase/α-glucosidase Inhibitor
Pedalitin is a dual inhibitor of tyrosinase (IC50 = 0.28 mM) and α-glucosidase (IC50 = 0.29 mM). This compound demonstrates significant biological activity in the regulation of melanin production and glucose metabolism. Pedalitin is suitable for research applications exploring skin pigmentation disorders and metabolic diseases. -
Endogenous Metabolite
11-dehydro-2,3-dinor Thromboxane B2 is an endogenous metabolite derived from the inactive metabolite TXB2 through the action of cytosolic aldehyde dehydrogenase and β-oxidation pathways. This compound plays a crucial role in the regulation of thromboxane biosynthesis and is implicated in various physiological and pathological processes. Elevated levels of 11-dehydro-2,3-dinor TXB2, observed in surgery-induced rat models of tendon overuse, suggest its potential utility in research related to inflammation and tissue repair mechanisms. -
Endogenous Metabolite
5α-Androstenone is an endogenous metabolite primarily recognized for its role as an odorous compound found in porcine adipose tissue. This steroidal compound is utilized in biological research to study its effects on pheromonal signaling and its potential influence on social and sexual behaviors in mammals. Its unique properties make it a valuable tool for investigations into olfactory signaling pathways and the biology of pheromones. -
Endogenous Metabolite
Glycerophospho-N-palmitoyl ethanolamine (GP-NPEA) is an endogenous metabolite and a metabolic precursor of palmitoyl ethanolamide (PEA). Research indicates that GP-NPEA levels decline in the cortex of chronic unpredictable stress (CUMS) rats, suggesting a potential link to disruptions in the endocannabinoid system associated with depression. This compound is valuable for studies examining metabolic pathways and neurobiological influences in mood disorders. -
Endogenous Metabolite
(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate is an endogenous metabolite known for its role in various physiological processes. This compound is involved in modulating neurotransmission and may influence pathways associated with neuroprotection and synaptic plasticity. It is valuable for research applications focused on metabolic profiling and neurochemical studies. -
Endogenous Metabolite
Trigalacturonic acid is an endogenous metabolite primarily involved in promoting plant cell growth and enhancing cell wall stability. It is known to improve plants' resilience to environmental stressors and is extensively utilized as a nutrient in plant cell culture applications. Additionally, trigalacturonic acid serves as a food additive, exhibiting thickening and gelling properties that are valuable in the food industry. -
Endogenous Metabolite
Ganglioside sialidase (AuSialidase S) functions as an endogenous metabolite that acts on gangliosides, facilitating the removal of sialic acid residues. This enzymatic activity plays a significant role in neuronal differentiation and is crucial for processes such as neurite outgrowth. AuSialidase S is valuable in research applications focused on neurobiology, particularly studies investigating neuronal development and associated signaling pathways. -
Endogenous Metabolite
1,3-Dimethyluracil is a pyrimidone derivative of uracil, serving as an endogenous metabolite in humans. This compound exhibits inhibitory activity against human carbonic anhydrases I and II, with Ki values of 316.2 μM and 166.4 μM, respectively. Its enzymatic inhibition profile makes it valuable for research applications involving carbonic anhydrase-related pathways and metabolic studies. -
Endogenous Metabolite
KSD 2405 is an endogenous metabolite that plays a significant role in various biochemical pathways. This compound is involved in metabolic processes and may influence cellular function and signaling. Its application in research includes the study of metabolic disorders, physiological regulation, and potential therapeutic interventions. -
Fungal Metabolite
Cerebroside D is a glycoceramide compound known for its immunomodulatory properties. It has been shown to enhance recovery from experimental colitis in mouse models, primarily through the modulation of activated T lymphocytes. This compound is of particular interest in research related to autoimmune diseases and inflammation. -
Endogenous Metabolite
SEP-227900 is a potent and orally bioavailable inhibitor of D-amino acid oxidase (DAO). It exhibits significant biological activity that may benefit conditions related to vitamin D metabolism and sunlight exposure. This compound holds promise for enhancing cancer prognosis and is applicable in research focusing on metabolic pathways and related diseases. -
Endogenous Metabolite
5-Methoxysalicylic acid (5-MeOSA) is an endogenous metabolite known for its role as a matrix in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis of oligonucleotides. When combined with spermine, 5-MeOSA enhances ionization efficiency, making it a valuable tool in biochemical research. Its applications extend to studying nucleic acid interactions and characterizing oligonucleotide structures, thereby facilitating advancements in genetic and molecular biology studies. -
Endogenous Metabolite
Dapagliflozin-3-O-β-D-glucuronide is an endogenous metabolite of Dapagliflozin, produced primarily by the enzyme uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9) in the liver and kidney. This compound plays a crucial role in the pharmacokinetics of Dapagliflozin, a selective inhibitor of sodium-glucose co-transporter 2 (SGLT2), which is utilized for improving glycemic control in type 2 diabetes management. Its study is significant in understanding drug metabolism and therapeutic efficacy in diabetic conditions. -
Endogenous Metabolite
Dihomo-γ-linolenic acid sodium is an endogenous metabolite classified as a 20-carbon ω-6 fatty acid. It exhibits notable anti-inflammatory and anti-proliferative activities, making it relevant for research involving lipid metabolism and cellular signaling. Notably, DGLA sodium has been shown to attenuate atherosclerosis in apolipoprotein E-deficient mouse models, highlighting its potential in cardiovascular research and inflammation studies. -
Fungal Metabolite
(-)-Cyclopenol is a fungal metabolite derived from the Australian marine fungus Aspergillus versicolor (MST-MF495). This compound exhibits significant biological activity, particularly in the inhibition of specific fungal species. It serves as a valuable tool for studying fungal metabolism and exploring potential antifungal applications in research. -
Endogenous Metabolite
6-Dehydroprogesterone is an endogenous metabolite derived from the microbial dehydrogenation of progesterone. This steroid compound is significant for studying steroid metabolism pathways, including microbial dehydrogenase activity and steroid biotransformation. Its unique properties make it a valuable tool for researchers investigating the biochemical roles of steroid metabolites.
