Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid characterized by the presence of stearic acid and adrenic acid at the sn-1 and sn-2 positions, respectively. This endogenous metabolite has been shown to demonstrate an inverse correlation with age in mitochondria extracted from human post-mortem hippocampus, suggesting its potential role in age-related mitochondrial function. It serves as a valuable tool for research into lipid metabolism and neuronal health. -
Endogenous Metabolite
Lantanose A is an oligosaccharide derived from the root of Lantana camara, serving as an endogenous metabolite. It exhibits significant biological activity and is of interest in various research applications, particularly in the study of plant metabolism and interactions with biological systems. Researchers may explore its potential benefits in understanding metabolic pathways and physiological responses in different organisms. -
Fungal Metabolite
Avellanin B is a fungal metabolite known for its pressor effects. It exhibits significant bioactivity that may modulate vascular resistance and blood pressure. This compound can be utilized in research focused on cardiovascular dysfunction and the physiological impacts of fungal metabolites. -
Endogenous Metabolite
Laidlomycin propionate is an endogenous metabolite that enhances weight gain and feed conversion efficiency in livestock. It is primarily used as a feed additive in cattle farming, demonstrating significant improvements in daily weight gain, feed intake, and carcass weight. Extensive research has highlighted its potential to reduce production costs and increase profitability within the cattle industry, although findings may vary across different studies in North America. -
Endogenous Metabolite
Diethylumbelliferyl phosphate (DEUP) acts as a selective and potent inhibitor of cholesterol esterase. This compound effectively disrupts steroidogenesis by inhibiting the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM. DEUP is valuable in research applications focused on cholesterol metabolism and steroid hormone synthesis. -
Endogenous Metabolite
Aspergillomarasmine A is a natural aminopolycarboxylic acid that functions as an inhibitor of class B metallo-β-lactamases (MBLs). It specifically inactivates these enzymes by chelating the essential Zn2+ cofactor, effectively promoting the degradation of zinc-deficient NDM-1 and enhancing the efficacy of β-lactam antibiotics. This compound serves as a selective Zn2+ scavenger, demonstrating broad potential for research applications aimed at understanding and overcoming β-lactam resistance in bacterial pathogens. -
Endogenous Metabolite
22:0 PC (1,2-Didocosanoyl-sn-glycero-3-phosphocholine) is an endogenous metabolite primarily acting as a lung surfactant. As an amphipathic phosphatidylcholine, it is mainly localized in the outer leaflets of biological membrane bilayers. This compound is crucial for maintaining alveolar stability and surface tension, making it valuable for research applications in pulmonary biology, membrane dynamics, and lipid metabolism studies. -
Endogenous Metabolite
LAPAO (Laurylamidopropyldimethylamine oxide) is an amphoteric surfactant known for its excellent biocompatibility and surface-active properties. It exhibits significant detergent and foam-enhancing capabilities, making it suitable for applications in personal care and household cleaning products. LAPAO maintains stability across a range of pH values and effectively removes dirt and grease, while also providing conditioning benefits that enhance the performance of skin and hair care formulations. -
Endogenous Metabolite
Hemi-Oxanthromicin A is a polyketide derived from the bacterium Streptomyces. This compound acts as an endogenous metabolite, exhibiting notable antibacterial activity. It is primarily utilized in research focused on microbial secondary metabolites and their potential therapeutic applications. -
Insect Pheromone
(Z)-10-Hexadecenal is an insect pheromone primarily involved in mediating attraction between mating partners. This compound has been identified as a fruit-type female pheromone derived from the abdominal tip extracts of female Dichocrocis punctiferalis. Its unique properties make it valuable for use in ecological studies and pest management research, facilitating investigations into insect behavior and communication. -
Endogenous Metabolite
(Z)-9-Heptadecenoic Acid is an endogenous metabolite classified as a monounsaturated fatty acid. This compound serves as a significant component of ruminant fat and milk, where its concentrations have been observed to negatively correlate with methane production in cattle on high-lipid diets. Research applications include studies on lipid metabolism, ruminant nutrition, and the mitigation of greenhouse gas emissions in livestock. -
Pheromone
Nonacosadiene is a natural pheromone derived from Drosophila melanogaster, functioning primarily as a chemical signal for communication among individuals. This compound plays a crucial role in mating behavior and social interaction within the species. Its unique properties make it valuable for research in behavioral ecology, chemical communication, and the study of pheromone mechanisms. -
Endogenous Metabolite
Propyl nicotinate, also known as nicotinic acid propyl ester, is an endogenous metabolite that serves as the propyl ester of niacin. It plays a crucial role in the biosynthesis of coenzymes NAD and NADP, which are essential for various metabolic processes. Propyl nicotinate is utilized in research focusing on metabolic regulation and coenzyme activity, contributing to the understanding of cellular respiration and energy metabolism. -
Endogenous Metabolite
Ozolinone is an endogenous metabolite derived from the biotransformation of the diuretic elkapin in mammals, primarily functioning as a potent diuretic agent. It exhibits significant diuretic properties across various species, making it valuable for research in renal physiology and fluid regulation studies. Its role in understanding metabolic pathways and the efficacy of diuretic compounds further supports its application in biochemical research. -
Endogenous Metabolite
(25R)-26-Hydroxycholest-4-en-3-one is an oxysterol and an important endogenous metabolite. It plays a significant role in the regulation of cholesterol metabolism and cellular signaling pathways. This compound is relevant for research applications related to lipid biology, cardiovascular diseases, and metabolic disorders. -
Endogenous Metabolite
9(R)-HODE cholesteryl ester is an endogenous metabolite associated with atherosclerotic lesions. This compound serves as a valuable standard for the analysis of chiral HODE cholesteryl esters, allowing for the investigation of lipid oxidation processes and their biochemical implications. Its utility in research extends to studies exploring the role of oxidized fatty acids in cardiovascular disease and metabolic disorders. -
Endogenous Metabolite
Phomosine D is an endogenous metabolite derived from the fungus Phomopsis. This compound demonstrates various biological activities, making it valuable for research into fungal metabolism and the ecological roles of secondary metabolites. Its unique profile aids in exploring potential applications in biomedical research and natural product chemistry. -
Endogenous Metabolite
8(R),9(S)-EET is an isomer of epoxyeicosatrienoic acid with a primary mechanism involving metabolism by cytosolic epoxide hydrolase (cEH). This compound demonstrates significant biological activity related to lipid signaling pathways and modulates vascular tone and inflammation. It serves as a valuable tool in research applications exploring cardiovascular biology and related metabolic processes. -
Endogenous Metabolite
POPi (phloridzin oxidation product i) is an endogenous metabolite produced by the oxidation of phloridzin, catalyzed by apple polyphenol oxidase. This compound exhibits DPPH radical-scavenging activity, making it a valuable tool in antioxidant research. Its role in studying oxidative stress and potential therapeutic applications enhances its utility in the exploration of metabolic pathways and antioxidant mechanisms. -
Endogenous Metabolite
4(Z),7(Z)-Decadienoic acid is an endogenous metabolite that functions as a fatty acid and is identified as a component of the cloacal gland secretion in the tuatara (Sphenodon punctatus). This compound may be utilized in studies investigating lipid metabolism, animal physiology, and chemical ecology. Its unique structure and biological role make it relevant for research into the chemical signaling pathways and evolutionary adaptations of reptiles. -
Endogenous Metabolite
ML262 is a potent inhibitor of hepatic lipid droplet formation, with an IC50 of 6.4 nM in murine AML-12 cells. This compound is significant in research related to non-alcoholic fatty liver disease, as it selectively targets lipid metabolism without inducing cytotoxicity at concentrations up to 33 μM. Additionally, ML262 does not interfere with fatty acid uptake at concentrations up to 50 μM, making it a valuable tool for studying lipid homeostasis and related metabolic disorders. -
Endogenous Metabolite
Lactosyl-C18-sphingosine is a bioactive sphingolipid that functions as a lysoganglioside, specifically a form of lactosylceramide without the fatty acyl group. It exhibits the ability to reduce the viability of human neutrophils in a concentration-dependent manner at low micromolar concentrations (1-50 μM). Unlike its counterpart, lactosylceramide, Lactosyl-C18-sphingosine does not affect protein synthesis or cell proliferation in cardiomyocytes, making it a unique tool for studying sphingolipid signaling and metabolism in various biological contexts. -
Endogenous Metabolite
N-Lauroyl-L-glutamic acid is an amino acid derivative targeting endogenous metabolic pathways. This compound exhibits anti-asthmatic properties and has demonstrated efficacy in reducing asthma symptoms in various studies. Its primary applications involve the potential management and suppression of respiratory diseases, offering prospects for enhanced patient quality of life in clinical settings. -
Endogenous Metabolite
Disperse Red 1 acrylate is an endogenous metabolite that acts as a crucial component in non-linear optical (NLO) materials. This compound is primarily utilized in research applications related to photonics and materials science, contributing to the development of advanced optical devices. Its unique properties make it suitable for exploring new methodologies in NLO applications. -
Endogenous Metabolite
8-Hydroxy loxapine is an oxidative metabolite of Loxapine, primarily known for its relatively low biological activity compared to its counterpart 7-OH-loxapine. This compound serves as a valuable tool in neurological research, particularly in studies related to the pharmacokinetics and metabolic pathways of antipsychotic medications. Its role as an endogenous metabolite allows for investigations into the physiological implications of Loxapine metabolism in various biological systems. -
Endogenous Metabolite
(±)-Geosmin is a natural organic compound known for its distinctive earthy aroma. It functions as an endogenous metabolite with significant roles in microbial metabolism. This compound is widely utilized in studies related to environmental monitoring, particularly for detecting soil and water pollution, as well as in the flavor and fragrance industries. -
Endogenous Metabolite
Glucoalyssin is an endogenous metabolite primarily known for its role as a major glucosinolate in Degenia velebitica. It exhibits significant antioxidant activity, contributing to the protective mechanisms in various biological systems. This compound is utilized in plant taxonomy research, aiding in the classification and study of plant species based on their glucosinolate profiles. Its unique properties make it valuable for studies focused on plant defense mechanisms and metabolic profiling. -
Endogenous Metabolite
Stearoyl serotonin is a hybrid compound designed to target the endogenous metabolite systems and is structurally derived from arachidonoyl serotonin. This compound is investigated for its ability to function as a dual antagonist of fatty acid amide hydrolase (FAAH) and the TRPV1 channel, which are critical pathways in the modulation of pain. Preliminary studies suggest that modifications to the arachidonoyl structure, such as the introduction of an 18-carbon stearoyl moiety, may influence TRPV1 channel activity; replacement with saturated fatty acids has demonstrated significant inhibition of capsaicin-induced activation. This positions stearoyl serotonin as a potential candidate for research into pain mechanisms and therapeutic applications. -
Endogenous Metabolite
11(Z),14(Z),17(Z)-Eicosatrienoic acid methyl ester is a naturally occurring metabolite found in the microalga Nannochloropsis. This compound exhibits notable biological activity and serves as a valuable research tool for studying metabolic pathways and the effects of environmental pollutants. Additionally, it can be isolated from diesel-contaminated soil, highlighting its relevance in environmental toxicology and bioremediation studies. -
Endogenous Metabolite
Carprazidil is a potent vasodilator primarily targeting the modulation of vascular smooth muscle tone. It demonstrates significant efficacy in suppressing severe hypertension and managing mild heart failure. Research applications include investigating the drug's cardiovascular effects and exploring its potential side effects, such as sodium retention and increased heart rate, as well as its impact on hirsutism in women. Notably, carprazidil does not adversely affect hematological parameters or liver and kidney function, making it a valuable compound for cardiovascular research. -
Endogenous Metabolite
Fluazuron is an insect growth regulator that targets the molting process in larvae of Amblyomma sculptum. Demonstrating 100% efficacy, Fluazuron rapidly absorbs and exhibits slow metabolism, making it a promising candidate for controlling the Brazilian spotted fever. Its effectiveness suggests potential applications in developing feed products designed to manage tick populations in free-living capybaras, contributing to effective pest management strategies. -
Endogenous Metabolite
Sarcinapterin is an L-glutamyl derivative of the coenzyme methanopterin, acting as a key endogenous metabolite. This compound plays a crucial role in methanogenic pathways and is primarily studied in the context of microbial metabolism, particularly in organisms like Methanosarcina barkeri. Its research applications extend to biochemical studies of methanogenesis and metabolic profiling in anaerobic environments. -
Endogenous Metabolite
(±)9-HODE cholesteryl ester is an endogenous metabolite derived from atherogenic processes, particularly identified within atherosclerotic lesions. This compound is formed through the Cu2+-catalyzed oxidation of low-density lipoprotein (LDL) and is further metabolized by 15-lipoxygenase (15-LO) in rabbit reticulocytes and human monocytes from cholesteryl linoleate, a predominant LDL component. Its relevance in lipid metabolism and atherosclerosis research makes it a valuable reagent for studies investigating cardiovascular diseases and oxidative stress mechanisms. -
Endogenous Metabolite
Lunine is an endogenous metabolite derived from the alkaloid Lunasia quercifolia. This compound demonstrates stability against various conditions, including acids, bases, oxidants, and reducing agents. Lunine can be utilized to study metabolic pathways and the biochemical roles of alkaloids in cellular processes. Its unique properties make it valuable for research in pharmacology and natural product chemistry. -
Endogenous Metabolite
Ala-Ala-Phe-AMC is a fluorogenic substrate primarily used for the detection of proteolytic activity. Its positively charged characteristics enhance its suitability for various biochemical assays, enabling researchers to investigate protease function in biological samples. This compound is valuable in studies related to protein turnover, cellular signaling, and disease mechanisms involving proteolysis. -
Endogenous Metabolite
D-2-Phosphoglyceric acid is a crucial endogenous metabolite involved in cellular energy metabolism and biosynthesis regulation. It plays an essential role in glycolysis and photosynthesis, contributing to the overall energy supply for cells. Additionally, D-2-Phosphoglyceric acid serves as a valuable biomarker for assessing metabolic status across various organisms in research applications. -
Endogenous Metabolite
BTPTT-4F is a non-fullerene acceptor-donor-acceptor (A-D-A) small molecular acceptor (SMA) with a unique ladder-type electron-deficient core, flexible alkyl chains, and a centrally fused ring structure. This compound exhibits significant potential in organic photovoltaic applications, particularly when blended with PM6, leading to enhanced solar cell performance. Its optimized optical properties and adjustable electronic energy levels contribute to improved thermal and photochemical stability, making BTPTT-4F a promising candidate for research in next-generation high-efficiency organic solar cells. -
Endogenous Metabolite
(S)-KT109 is a selective inhibitor of diacylglycerol lipase β (DAGLβ), exhibiting an IC50 of 39.81 nM. This compound demonstrates lower inhibitory effects on DAGLα, with an IC50 of 794.3 nM, and shows reduced activity against α/β-amidase domain-containing 6 (ABHD6) at an IC50 of 630.9 nM. (S)-KT109 is valuable for research investigating the roles of endocannabinoids in various biological pathways, particularly those involving lipids and neurobiology. -
Endogenous Metabolite
(+/-)-Adomeglivant is a selective glucagon receptor antagonist that exerts hypoglycemic effects by inhibiting glucagon signaling. This compound is effective in lowering blood glucose levels in both healthy individuals and patients with type 2 diabetes. Its use has been associated with a reduction in fasting and postprandial glucose, alongside a reversible increase in aminotransferases. The potential of (+/-)-Adomeglivant as an inhibitory approach in the management of type 2 diabetes merits further investigation in clinical studies to fully assess its benefits and risks. -
Endogenous Metabolite
5(S)-HETrE is a metabolite derived from the ω-6 fatty acid γ-linolenic acid, playing a significant role in lipid metabolism. Elevated levels of 5(S)-HETrE have been observed in serum from obesity mouse models, suggesting its potential involvement in metabolic disorders. This compound serves as a valuable tool for research into obesity, inflammation, and related metabolic pathways. -
Endogenous Metabolite
(Z)-Octadec-13-enoic acid, also known as cis-13-Octadecenoic acid, is a monounsaturated fatty acid that serves as an endogenous metabolite. This compound is primarily derived from bovine milk fat and plays a significant role in various biological processes, including lipid metabolism and cell signaling. It is valuable for research applications that investigate fatty acid profiles and their physiological effects in different biological systems. -
Endogenous Metabolite
(R)-Coriolic acid is an endogenous metabolite derived from the metabolism of linoleic acid through the action of lipoxygenase. It has been identified in the supernatants and membranes of cultured bovine endothelial cells, reflecting its role in COX-mediated pathways. Additionally, (R)-Coriolic acid is recognized as a weak inhibitor of U-46619-induced platelet aggregation, with an IC50 of 2.7 µM. This compound is valuable for research on lipid metabolism, cardiovascular function, and platelet biology. -
Endogenous Metabolite
2-Hydroxy-3-(palmitoyloxy)propyl stearate is a diacylglycerol featuring palmitic acid at the sn-1 position and stearic acid at the sn-3 position. This endogenous metabolite is identified in palm-derived diacylglycerols, including those from palm oil and palm stearin, as well as in extracts from wheat bran and brewer’s spent grain. It holds potential for research in lipid metabolism and may provide insights into nutritional and health-related studies involving dietary fats. -
Insect Sex Pheromone
11-Dodecenyl acetate is an insect sex pheromone that plays a crucial role in the attraction behavior of male moths. This compound is primarily utilized in entomological research to study mating behaviors and to develop pest control strategies by disrupting mating patterns. Its application extends to ecological studies focusing on species interactions and population dynamics within insect communities. -
Endogenous Metabolite
Yokonoside is an endogenous metabolite with potential cardioprotective properties derived from Aconitum japonicum. This cardiac glycoside demonstrates antioxidant activity, making it relevant for research into oxidative stress and cardiac health. It is valuable for studies investigating the biological effects of natural compounds in cardiovascular and metabolic research. -
Endogenous Metabolite
9Z,11E,13Z-Octadecatrienoic acid methyl ester, also known as methyl punicate, is an endogenous metabolite derived from Punica granatum L. This fatty acid methyl ester demonstrates significant antitumor activity by disrupting the tumor cell cycle, modulating drug resistance, and inhibiting angiogenesis. Its unique properties make it a valuable tool for research in cancer therapeutics and metabolic studies. -
Endogenous Metabolite
Isariin C is a flavonoid glycoside that functions as an endogenous metabolite with notable antioxidant activity. Primarily, it has been shown to activate angiogenesis, making it a valuable tool in research related to vascular development and regulation. Additionally, Isariin C exhibits insecticidal properties in various insect species, positioning it as a potential candidate for studies in pest management and toxicology. -
Endogenous Metabolite
(R,R,S)-GAT107 is a potent positive allosteric modulator of the α7 nicotinic receptors, exhibiting robust agonistic activity. This compound primarily functions through its (+)-isomer, demonstrating significant biological effects, while the (-)-isomer shows no such activity. Research indicates that (R,R,S)-GAT107 is currently recognized as the most effective ago-PAM for α7 nicotinic receptors, suggesting promising avenues for further investigation in vivo. Potential applications include studies related to cognitive enhancement and neuroinflammation. -
Endogenous Metabolite
9(R)-HODE is a monohydroxy fatty acid and an endogenous metabolite of linoleic acid, generated through the enzymatic actions of cyclooxygenase (COX) and lipoxygenase (LO). This compound is known to promote chemotaxis and elevate the expression of chemokine receptors CCR9 and CXCR4 in immune cells. Additionally, 9(R)-HODE effectively inhibits interleukin-6 (IL-6) release in primary human monocytes and suppresses CD3α- and CD28-induced proliferation in isolated human peripheral blood lymphocytes at a concentration of 25 μg/mL, making it a valuable tool for studying immune responses and inflammatory processes. -
Endogenous Metabolite
(+)-Adomeglivant is a selective antagonist of the glycogenotropin receptor, exhibiting significant glucose-lowering activity. Its ability to effectively reduce fasting blood glucose levels makes it a valuable tool for studying hyperglycemia mechanisms in type 2 diabetes. Additionally, the antagonistic properties of (+)-Adomeglivant may complicate assessments of the metabolic effects associated with postprandial hyperglycemia, providing insights into the intricacies of metabolic regulation in diabetic conditions.
