Catalog No.
Product Name
Application
Product Information
Citations
-
Bacterial Inhibitor
Ceftezole is a broad-spectrum cephem antibiotic that effectively targets both gram-positive and gram-negative bacteria. Its primary mechanism involves inhibiting bacterial cell wall synthesis, making it valuable in combating various bacterial infections. Additionally, Ceftezole acts as an alpha-glucosidase inhibitor, demonstrating potential in in vivo anti-diabetic applications. It is suitable for use in microbiological research and studies related to diabetes management. -
Bacterial Inhibitor
Ceftezole sodium is a broad-spectrum cephem antibiotic primarily targeting various gram-positive and gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Additionally, ceftezole sodium demonstrates alpha-glucosidase inhibition, contributing to its in vivo anti-diabetic effects. This compound is relevant for research in microbial resistance and diabetes therapeutic development. -
Endogenous Metabolite, Precursor of Edoxudine
2'-Deoxyuridine is a nucleoside that serves as a precursor for the antiviral agent Edoxudine and plays a crucial role in nucleotide metabolism. It has been shown to increase chromosome breakage and reduce thymidylate synthase activity, highlighting its significance in DNA synthesis research. Additionally, 2'-deoxyuridine has demonstrated the ability to reduce microglial activation and improve oxidative stress in models of Aβ25-35-induced brain injury, making it a valuable tool for Alzheimer's disease research. -
Endogenous Metabolite
Cholic acid sodium is an endogenous metabolite that serves as a primary bile acid synthesized in the liver, typically conjugated with glycine or taurine. It plays a crucial role in facilitating fat absorption and promoting cholesterol excretion. Cholic acid sodium is also orally active, making it valuable for studies related to lipid metabolism and gastrointestinal function. -
Endogenous Metabolite
D-Mannose is a naturally occurring C-2 superpolymer of glucose that functions as an endogenous metabolite. It exhibits anti-inflammatory and antitumor properties, contributing to immune regulation and offering potential therapeutic benefits. D-Mannose is utilized in various research applications aimed at understanding its roles in immunology and cancer biology. -
Endogenous Metabolite
L-(+)-Arabinose is an endogenous metabolite that selectively inhibits intestinal sucrase activity through a noncompetitive mechanism. This inhibition effectively suppresses the increase in plasma glucose levels following sucrose ingestion, making it a valuable tool for research on carbohydrate metabolism and diabetes. Its role in modulating sugar absorption positions L-(+)-Arabinose as a significant compound for studies focused on metabolic disorders and intestinal enzyme activity. -
Endogenous Metabolite
Oxalic acid is a strong dicarboxylic acid that functions as an endogenous metabolite. It is involved in various biological processes and can serve as an analytical reagent and general reducing agent in laboratory settings. Its applications extend to biochemical research, where it is utilized in studies related to plant metabolism and environmental stress responses. -
Endogenous Metabolite, L-enantiomer of Isoleucine
L-Isoleucine is the L-enantiomer of isoleucine and an essential branched-chain amino acid. It functions as a pivotal endogenous metabolite in various organisms, including humans, animals, plants, and microorganisms. L-Isoleucine plays a critical role in modulating the inflammatory response, contributing to the protection against pathogens both in vivo and in vitro. This compound is often utilized in studies exploring metabolic pathways, protein synthesis, and immune responses. -
Endogenous Metabolite
NSC 42196 is an endogenous metabolite that plays a significant role in cellular metabolism. It is involved in various biochemical pathways and is primarily used for the study of metabolic processes and the regulation of physiological responses. Research applications include investigations of metabolic disorders and the exploration of homeostatic mechanisms in cellular function. -
Endogenous Metabolite
L-Threonine is an essential amino acid and a key endogenous metabolite that plays a critical role in protein synthesis and metabolism. It is involved in various biological processes, including immune function and central nervous system function. L-Threonine is commonly utilized in nutritional studies, metabolic research, and formulations for animal feed and supplements. -
Endogenous Metabolite
β-Alanine is a non-essential amino acid that serves as a precursor for the synthesis of carnosine, an important intracellular buffer. This metabolite is involved in maintaining pH homeostasis within cells, particularly in muscle tissues during intense physical activity. β-Alanine is widely utilized in biochemical research and studies focusing on muscle performance and fatigue. -
Endogenous Metabolite
Myristic acid is a saturated 14-carbon fatty acid that acts as an endogenous metabolite. It exhibits anti-inflammatory activity primarily through the NF-κB signaling pathway. In addition to its anti-inflammatory properties, myristic acid also demonstrates antibacterial and analgesic effects, making it valuable for research in inflammation, immunity, and pain management. -
Endogenous Metabolite
ATP disodium salt hydrate (Adenosine 5'-triphosphate disodium salt hydrate) is an essential endogenous metabolite involved in cellular energy storage and metabolism. It functions as a primary energy currency, powering metabolic processes and serving as a coenzyme in various biochemical reactions. Additionally, ATP disodium salt hydrate plays a critical role in cellular signaling pathways related to immune responses and inflammation, making it a valuable reagent for research in these areas. -
Mutant IDH2 Inhibitor
Enasidenib mesylate is a selective inhibitor of mutant isocitrate dehydrogenase 2 (IDH2) enzymes, demonstrating potent and reversible binding. It primarily exerts its biological activity by altering the metabolism of 2-hydroxyglutarate, thus affecting cellular processes associated with cancer progression. This compound is utilized in research focused on hematologic malignancies, particularly those driven by IDH2 mutations. -
Endogenous Metabolite
Lecithin is an endogenous metabolite and a conventional source of phospholipids, primarily known for its role in membrane architecture. It plays a critical role in modulating the fatty acid composition and microstructure of cellular membranes in animal cells. Lecithin is widely used in research applications involving cell membrane studies, lipid metabolism, and the development of lipid-based formulations. -
Endogenous Metabolite
Isorhamnetin is a flavonoid compound that acts as an endogenous metabolite. It exhibits significant biological activity by directly inhibiting MEK1 and PI3K, contributing to its potential role in suppressing skin cancer. This compound is useful in research applications focused on cancer biology and the investigation of signaling pathways involved in tumorigenesis. -
DHFR Inhibitor
Proguanil is a potent dihydrofolate reductase (DHFR) inhibitor, primarily utilized in antimalarial research. Upon administration, it is metabolized to Cycloguanil, its active form, enhancing its efficacy against Plasmodium species. This compound is essential for studying the biochemical pathways of folate metabolism and developing therapeutic strategies against malaria. -
Endogenous Metabolite
L-Histidine (monohydrochloride) is an essential amino acid that serves as a critical endogenous metabolite, particularly for infants. It plays a role in various biological processes and functions as an inhibitor of mitochondrial glutamine transport. This compound is frequently used in research applications involving amino acid metabolism, cellular signaling pathways, and neurotransmitter synthesis. -
Endogenous Metabolite
2-Methylpentanedioic acid is an endogenous metabolite derived from succinic acid, an important intermediary in the citric acid cycle. This compound plays a role in metabolic pathways and energy production within cells. It is utilized in research applications focused on metabolic profiling and the study of metabolic disorders. -
Endogenous Metabolite
3-Methylsalicylic acid, also known as o-Cresotic acid, primarily functions as an endogenous metabolite. This compound demonstrates notable fibrinolytic activity by activating the fibrinolytic system in human plasma, making it valuable in studies related to blood clotting and wound healing. Additionally, 3-Methylsalicylic acid can serve as a synthetic intermediate for the production of various chemical entities and has been observed to inhibit feeding behaviors in midges, highlighting its potential for ecological research applications. -
Monoamine Oxidase Inhibitor
Pheniprazine hydrochloride is a potent monoamine oxidase inhibitor that plays a significant role in modulating neurotransmitter levels. This compound is primarily utilized in depression research, offering insights into the biochemical pathways associated with mood regulation. Its long-acting properties make it a valuable reagent for studies investigating monoamine metabolism and related neuropsychological disorders. -
α-glucosidase/α-amylase Inhibitor
2-Hydroxyquinoline is a selective inhibitor of α-glucosidase and α-amylase, exhibiting IC50 values of 64.4 µg/mL and 130.5 µg/mL, respectively. This compound is valuable for investigating carbohydrate metabolism and can be utilized in research related to diabetes management and treatment strategies. Its inhibitory effects contribute to a deeper understanding of enzymatic roles in glucose absorption and metabolism. -
Endogenous Metabolite
Methyl 2-furoate is an endogenous metabolite that serves as a versatile building block in organic synthesis. It is primarily utilized in the production of cis-fused 5-oxofuro[2,3-b]furans and has applications in the preparation of sesquiterpene lactones. Its significance in chemical research highlights its role in developing complex biochemical compounds and exploring metabolic pathways. -
Ferroptosis Inhibitor
Isoeugenol acetate is a ferroptosis inhibitor derived from isoeugenol. This compound has been shown to modulate cell death mechanisms associated with oxidative stress, making it a valuable tool for investigating ferroptosis in various biological contexts. Its applications extend to research in cancer biology, neurodegenerative diseases, and other conditions where ferroptosis plays a critical role. -
endogenous metabolite
3-Hydroxybenzoic acid is an endogenous metabolite that acts as an agonist for GPR81 and GPR109A. This compound plays a significant role in modulating stress responses and contributes to anti-inflammatory and analgesic mechanisms. It is a valuable reagent for research exploring inflammation and pain pathways, as well as the physiological effects of metabolic signaling in various biological systems. -
Herbicide
Quinoline-8-carboxylic acid functions as a herbicide, targeting various plant growth processes. This compound exhibits inhibitory activity against specific enzymes involved in plant metabolism, making it effective in controlling unwanted vegetation. Its applications extend to agricultural research focused on weed management and the development of environmentally friendly herbicide formulations. -
Endogenous Metabolite
2',4'-Dimethylacetophenone is an endogenous metabolite that serves as a key intermediate in various biochemical pathways. Due to its structural properties, it has been implicated in studies related to metabolic processes and can be utilized as a reference standard in metabolomics research. Its role in cellular metabolism makes it valuable for investigating metabolic dysregulation and potential biomarkers in disease states. -
Insect Pheromone
(E,E)-10,12-Hexadecadienol is an insect pheromone that serves as a chemical signal for female legume pod borer moths. This compound plays a crucial role in mating and reproductive behaviors, making it valuable for research in insect olfaction and behavioral ecology. It is frequently used in studies aimed at pest control and integrated pest management strategies. -
Endogenous Metabolite
Normetanephrine is an endogenous metabolite primarily involved in the modulation of catecholamine activity. It serves as a biological marker for conditions such as hypertension and can be utilized in research focused on cardiovascular diseases and endocrine disorders. Its presence in cerebrospinal fluid makes it a valuable target for studying neurochemical environments related to autonomic regulation. -
Drug Metabolite
10-Undecen-1-ol is a drug metabolite derived from ricinoleic acid, serving as a valuable comonomer for the synthesis of functionalized polymers. This compound plays an essential role in the design of novel materials and biochemical applications, enabling the incorporation of various functional groups to enhance material properties. Its utility in chemical research positions it as a key reagent for studies involving drug metabolism and polymer chemistry. -
Herbicide
Chloranocryl is a selective herbicide primarily utilized for controlling early growth stages of various plant species. It exhibits strong herbicidal activity against Brassica rapa while demonstrating lower activity against rice. This compound is valuable in herbicide research for developing effective weed management strategies in agricultural applications. -
Endogenous Metabolite
Tyramine hydrochloride is an endogenous metabolite known for its role in regulating blood pressure through its action on catecholamine release. This compound is naturally present in the body and occurs in various food sources. It is utilized in research applications related to cardiovascular physiology and neurological studies, particularly in investigations of neurotransmitter dynamics and hypertension mechanisms. -
AhR Activator
Benzyl butyl phthalate is an aryl hydrocarbon receptor (AhR) activator that plays a significant role in cellular signaling. It has been shown to promote the migration and invasion of hemangioma (HA) cells through the upregulation of Zeb1. In breast cancer cells, Benzyl butyl phthalate activates the SPHK1/S1P/S1PR3 pathway, contributing to the formation of metastasis-initiating breast cancer stem cells (BCSCs). This compound is instrumental for research in cancer biology and cellular signaling. -
Natural Products
β,β-Trehalose is an analog of trehalose that functions primarily as a carbohydrate. It has been shown to support the growth of shoot tips in Cuscuta, making it valuable for research in plant physiology and development. Additionally, β,β-Trehalose is susceptible to hydrolysis by nonspecific β-glucosidase, which may have implications for studying enzymatic processes in various biological systems. -
Endogenous Metabolite
5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite primarily associated with serotonin metabolism. This compound plays a crucial role in various physiological functions, including mood regulation and gastrointestinal activity. It is utilized in research applications involving neurobiology, pharmacology, and metabolic studies to better understand serotonin-related pathways and their implications in health and disease. -
Endogenous Metabolite
DL-Glyceraldehyde 3-phosphate is a critical endogenous metabolite that serves as an intermediate in glycolysis and gluconeogenesis pathways. This compound exhibits potent inhibitory effects on the growth of Escherichia coli, highlighting its potential role in microbiological research. Additionally, DL-Glyceraldehyde 3-phosphate acts as a competitive inhibitor of acyltransferase, making it valuable for studies on metabolic regulation and enzyme kinetics. -
Furazolidone Metabolite
3-Amino-2-oxazolidinone (AOZ) is a metabolite of the antibiotic furazolidone. It serves as a reliable biomarker for detecting furazolidone residues in biological matrices, facilitating studies on drug metabolism and elimination. Due to its oral bioavailability, AOZ plays a significant role in pharmacokinetic and toxicological research applications, particularly in food safety and veterinary medicine. -
IDO1 Inhibitor
2-Hydrazinobenzothiazole is a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 8 μM. This compound targets the heme group of IDO1 via hydrazine interactions, thereby modulating immune responses. It is primarily utilized in research related to immune system disorders and therapeutic interventions aimed at enhancing immune function. -
α-glucosidase Inhibitor
3,4-Methylenedioxychalcone is an α-glucosidase inhibitor with a reported IC50 of 1870 μM. This compound is relevant for research applications focused on type 2 diabetes, as it may help modulate carbohydrate metabolism by delaying the breakdown of complex carbohydrates. Its potential to influence glucose absorption can be valuable for studies aimed at understanding and treating metabolic disorders. -
Endogenous Metabolite
L-Cystathionine is a nonprotein thioether and a crucial endogenous metabolite involved in the metabolism of sulfur-containing amino acids. It exhibits protective effects against homocysteine-induced, mitochondria-dependent apoptosis in human vascular endothelial cells (HUVECs), highlighting its significance in cardiovascular health. Its role in cellular processes makes L-Cystathionine an important compound for researching cardiovascular protection and related metabolic pathways. -
Ectoparasiticide
Sulfiram is an ectoparasiticide that functions primarily as a weak inhibitor of aldehyde dehydrogenase (ALDH). It is utilized in the investigation of scabies, providing a valuable tool for understanding the biochemical pathways involved in ectoparasitic infections. Additionally, Sulfiram's inhibitory properties make it relevant for research exploring ALDH-related metabolic processes. -
Herbicide
2,4-D (2,4-dichlorophenoxyacetic acid) is a selective herbicide primarily targeting broad-leaved weeds. It exerts its biological activity by inhibiting DNA and protein synthesis, which disrupts normal plant growth and development. Additionally, 2,4-D has been shown to induce apoptosis, making it useful for research applications in plant biology and herbicide effectiveness studies. -
Endogenous Metabolite
Phenyramidol Hydrochloride is an endogenous metabolite known for its anticoagulant and analgesic properties. It enhances the sensitivity of detection in biological samples, making it a valuable tool for quantitative analysis through electrochemical oxidation in aqueous media. The use of an amino-functionalized multi-walled carbon nanotube-modified glassy carbon electrode has demonstrated a significant increase in current peak for the effective detection of Phenyramidol Hydrochloride. This compound is essential for research applications involving pharmacokinetics and metabolic profiling. -
Monoamine Oxidase Inhibitor
Nialamide is a non-selective inhibitor of monoamine oxidase (MAO), playing a critical role in regulating reactive oxygen species (ROS) production. This compound has been shown to induce hyperkinesis in animal models, enhance the anticonvulsant effects of Diphenylhydantoin in mice, increase rectal temperature, and potentiate the pressor response to Norepinephrine. Nialamide is valuable for research related to depression, inflammatory diseases, neurodegenerative disorders, and hypertension. -
Endogenous Metabolite
2-Oxobutanoic acid is an endogenous metabolite involved in various metabolic pathways, particularly in the enzymatic cleavage of cystathionine. This compound serves as a key intermediate in the transsulfuration pathway, contributing to the synthesis of cysteine and other important metabolites. Its biological activity makes it relevant for research into metabolic disorders and the regulation of sulfur amino acid metabolism. -
PPARγ Agonist
AI 3-25755 is a potent agonist of peroxisome proliferator-activated receptor gamma (PPARγ). This compound demonstrates significant biological activity in modulating PPARγ pathways, making it valuable for research into metabolic disorders. AI 3-25755 is particularly relevant for studies investigating mechanisms underlying opioid abuse and smoking cessation, providing insights into addiction and withdrawal processes. -
Ferroptosis Inducer
WMK-1 is a 1,2,4,5-tetraoxane derivative that functions as a potent ferroptosis inducer. It exhibits significantly greater cytotoxicity towards cancer cells compared to non-cancerous cells, effectively triggering ferroptosis in both cancer cells and cancer stem cells. This compound is valuable for research focused on cancer biology and therapeutic strategies targeting ferroptosis. -
SGK1 Inhibitor
SGK1-IN-9 is an inhibitor of serum/glucocorticoid-regulated kinase 1 (SGK1). This compound exhibits potential anti-cancer activity by modulating cell survival pathways and influencing tumor cell proliferation. It is suitable for use in cancer research to investigate the role of SGK1 in various malignancies and explore therapeutic strategies targeting this kinase. -
Fungal Metabolite
Chrodrimanin H is a sesquiterpenoid compound derived from the fungus Talaromyces primulinus H21. This metabolite effectively inhibits lipopolysaccharide-induced nitric oxide production in immune cells, showcasing an IC50 value of 24.71 μM. Chrodrimanin H is of interest in research exploring immune modulation and the role of fungal metabolites in inflammation-related pathways. -
Ferroptosis Inducer
WMK-2 is a 1,2,4,5-tetraoxane derivative that functions as a ferroptosis inducer, demonstrating broad-spectrum anticancer activity. Its mechanism involves the generation of hydroxyl radicals and lipid reactive oxygen species (ROS), leading to ferroptosis in cancer cells and cancer stem cells. This compound serves as a valuable tool for research focused on cancer biology and therapeutic strategies targeting ferroptosis.
