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Chrodrimanin H

Catalog No.: B21848
Fungal Metabolite
Chrodrimanin H is a sesquiterpenoid compound derived from the fungus Talaromyces primulinus H21. This metabolite effectively inhibits lipopolysaccharide-induced nitric oxide production in immune cells, showcasing an IC50 value of 24.71 μM. Chrodrimanin H is of interest in research exploring immune modulation and the role of fungal metabolites in inflammation-related pathways.
Chrodrimanin H 1446801-59-7 Fungal Metabolite
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionChrodrimanin H is a sesquiterpenoid compound derived from the fungus Talaromyces primulinus H21. This metabolite effectively inhibits lipopolysaccharide-induced nitric oxide production in immune cells, showcasing an IC50 value of 24.71 μM. Chrodrimanin H is of interest in research exploring immune modulation and the role of fungal metabolites in inflammation-related pathways.
Product Information
Catalog NumB21848
FormulaC25H32O6
Molecular Weight428.52
CAS Number1446801-59-7
SMILESC[C@@]12[C@@]3([H])[C@@](OC4=CC(O)=C(C(O[C@@H](C5)C)=O)C5=C4C3)([C@H](C[C@@]1([H])C(C)(C(CC2)=O)C)O)C
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Natural Products
Metabolism > Endogenous Metabolite