Dabrafenib carboxylic acid

Catalog No.: A73534
Endogenous Metabolite
Dabrafenib carboxylic acid is the carboxylate metabolite of dabrafenib, primarily functioning as an endogenous metabolite. This compound retains the capacity to modulate signaling pathways associated with MAPK/ERK pathway alterations. It serves as a valuable tool for studying the pharmacokinetics and biological effects of dabrafenib in cancer research, particularly in the context of melanoma and other tumors with BRAF mutations.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDabrafenib carboxylic acid is the carboxylate metabolite of dabrafenib, primarily functioning as an endogenous metabolite. This compound retains the capacity to modulate signaling pathways associated with MAPK/ERK pathway alterations. It serves as a valuable tool for studying the pharmacokinetics and biological effects of dabrafenib in cancer research, particularly in the context of melanoma and other tumors with BRAF mutations.
Product Information
Catalog NumA73534
FormulaC23H18F3N5O4S2
Molecular Weight549.55
CAS Number1195873-54-1
SMILESO=C(C(C)(C)C1=NC(C2=CC=CC(NS(=O)(C3=C(F)C=CC=C3F)=O)=C2F)=C(C4=CC=NC(N)=N4)S1)O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2