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Akt



18 Item(s)

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Catalog No. Product Name Product Information
A11287

A-443654

A-443654, a specific Akt inhibitor, interferes with mitotic progression and bipolar spindle formation. Learn More
A11034

A-674563

A-674563 is a B/Akt inhibitor with an IC50 of 14 nM and also shows inhibitory activity against PKA and CDK2 with IC50 of 16 and 46 nM, respectively. Learn More
A11286

AKT inhibitor VIII (AKTI-1/2)

AKT inhibitor VIII is a cell-permeable and reversible quinoxaline compound that potently and selectively inhibits Akt1/Akt2 activity (IC50 = 58 nM, 210 nM, and 2.12 ?M for Akt1, Akt2, and Akt3, respectively, in in vitro kinase assays). Learn More
A10094

AT7867

AT7867 is a novel and potent inhibitor of both AKT and the downstream kinase p70 S6 kinase (p70S6K) and also of protein kinase A. Learn More
A15006

AT7867 2HCl

AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively, little activity outside the AGC kinase family. Learn More
A11759

AZD5363

AZD5363 is a potent inhibitor of AKT with pharmacodynamic activity in vivo, has potential to treat a range of solid and hematologic tumors as monotherapy or a combinatorial agent. Learn More
A11031

CCT128930

CCT128930 is an ATP-competitive AKT inhibitor that is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA, achieved by targeting a single amino acid difference. Learn More
A13460

Deguelin

Deguelin is a natural product that displays profound antiproliferative activity. Learn More
A11246

GDC-0068

GDC-0068 is an ATP-competitive small molecule inhibitor of all three isoforms of Akt Learn More
A11030

GSK690693

GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor. Learn More
A10453

Honokiol

Honokiol is a lignan present in the cones, bark, and leaves of Magnolia grandiflora that has shown pro-apoptotic effects in melanoma, sarcoma, myeloma, leukemia, bladder, lung, prostate, oral squamous cell carcinoma and colon cancer cell lines. Learn More
A12877

KP372-1

KP372-1 is a synthetic small molecule AKT inhibitor. Learn More
A10003

MK-2206 2HCl

MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively. Learn More
A10709

Perifosine (NSC-639966)

Perifosine (also KRX-0401) acts as an Akt inhibitor and a PI3K inhibitor. Learn More
A11024

PF-04691502

PF-04691502 is a PI3K/mTOR kinase inhibitor, is also an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K/mTOR signaling pathway. Learn More
A11032

PHT-427

PHT-427 is a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Learn More
A13210

Triciribine

Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt. Learn More
A11033

Triciribine phosphate (NSC-280594)

Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation. Learn More

18 Item(s)

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Akt

Minimal Price: $40.00