Isobavachalcone

Catalog No.: A11453
Akt inhibitor
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM).
Grouped product items
Size Price Stock Qty
1mg
$35.00
In stock
5mg
$50.00
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10mg
$85.00
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25mg
$190.00
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50mg
$285.00
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100mg
$430.00
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500mg
$975.00
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10mM * 1mL in DMSO
$55.00
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM).
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A11453
Formula C20H20O4
Molecular Weight 324.37
CAS Number 20784-50-3
SMILES O=C(/C=C/C1=CC=C(C=C1)O)C2=CC=C(C(C/C=C(C)\C)=C2O)O
Synonyms Corylifolinin; Isobacachalcone
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 56 mg/mL (172.64 mM)
Water Insoluble
Ethanol 56 mg/mL (172.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.83 mL 154.14 mL 308.29 mL
0.5 mM 6.17 mL 30.83 mL 61.66 mL
1 mM 3.08 mL 15.41 mL 30.83 mL
5 mM 0.62 mL 3.08 mL 6.17 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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