Isobavachalcone

Catalog No.: A11453

Akt inhibitor

Isobavachalcone

Isobavachalcone Chemical Structure

CAS NO. 20784-50-3

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM).

Availability: In stock

Package Price Qty
5 mg
$72.00
10 mg
$124.00
50 mg
$368.00
100 mg
$736.00
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Biological Activity

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM).
In vitro DMSO 56 mg/mL (172.64 mM)
Water Insoluble
Ethanol 56 mg/mL (172.64 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.83 mL 154.14 mL 308.29 mL
0.5 mM 6.17 mL 30.83 mL 61.66 mL
1 mM 3.08 mL 15.41 mL 30.83 mL
5 mM 0.62 mL 3.08 mL 6.17 mL

*The above data is based on the productmolecular weight 324.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11453
Actions Inhibitor
CAS No. 20784-50-3
Formula C20H20O4
M. Wt 324.37
Solubility DMSO
Purity >98%
Synonyms Corylifolinin; Isobacachalcone
SMILES O=C(/C=C/C1=CC=C(C=C1)O)C2=CC=C(C(C/C=C(C)\C)=C2O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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