TIC10 isomer

Catalog No.: A12720

AKT inhibitor‎

TIC10 isomer Chemical Structure

CAS NO. 41276-02-2

TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics.

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$200.00
10mM * 1mL in DMSO
$79.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics.
Targets
Akt ERK
In vitro DMSO 11 mg/mL (28.46 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.87 mL 129.37 mL 258.73 mL
0.5 mM 5.17 mL 25.87 mL 51.75 mL
1 mM 2.59 mL 12.94 mL 25.87 mL
5 mM 0.52 mL 2.59 mL 5.17 mL

*The above data is based on the productmolecular weight 386.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12720
Actions Inhibitor
M. Wt 386.5
Formula C24H26N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 41276-02-2
Synonyms TIC 10, TIC-10
SMILES CC1=CC=CC=C1CN2C3=C(CN(CC3)CC4=CC=CC=C4)C(=O)N5C2=NCC5

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