France
You have no items in your shopping cart.
Publications citing Adooq Products
Chemical Information
| Catalog Num | A10453 |
|---|---|
| Actions | N/A |
| M. Wt | 266.3 |
| Formula | C18H18O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 35354-74-6 |
| Synonyms | houpa, hnk |
| SMILES code | C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C |
| Chemical Name | 2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol |
Description |
Honokiol is a lignan present in the cones, bark, and leaves of Magnolia grandiflora that has shown pro-apoptotic effects in melanoma, sarcoma, myeloma, leukemia, bladder, lung, prostate, oral squamous cell carcinoma and colon cancer cell lines. | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C)* | In vitro | DMSO | 53 mg/mL (198.99 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.55 mL | 187.76 mL | 375.52mL |
| 0.5 mM | 7.51 mL | 37.55 mL | 75.1 mL |
| 1 mM | 3.76 mL | 18.78 mL | 37.55 mL |
| 5 mM | 0.75 mL | 3.76 mL | 7.51 mL |
*The above data is based on the productmolecular weight 266.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Ordering online
To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.
To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.
When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards. We will then liaise with you or your purchasing department to confirm the order.
Found your products but not ready to order?
Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.
Ordering offline
You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order. Our contact details are:
- Tel: 866-930-6790
- Fax: 323-606-8156
- Email: [email protected]
We require the following information to process your order:
- The catalog number for each product.
- Your email address or fax number.
- Your name and telephone number.
- Shipping address and billing address.
- Purchase order numbers.
Similar product(s)
Special Price Starting at:
€38.48
PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2. ...
Special Price Starting at: €38.48
Special Price Starting at:
€76.95
BIX 02189 is a selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1 and other closely related kinases respectively. ...
Special Price Starting at: €76.95
Special Price Starting at:
€203.30
Refametinib, also known as RDEA119, BAY 86-9766, is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity. ...
Special Price Starting at: €203.30
Special Price Starting at:
€133.00
Cobimetinib is a potent, highly selective inhibitor of MEK1/2. ...
Special Price Starting at: €133.00
Special Price Starting at:
€34.20
AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor that inhibits growth and survival of MM cells and cytokine-induced osteoclast differentiation. ...
Special Price Starting at: €34.20
Special Price Starting at:
€76.95
VRT752271 is a pyrrole inhibitors of ERK protein kinase. ...
Special Price Starting at: €76.95
Special Price Starting at:
€209.00
RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineoplastic activity. ...
Special Price Starting at: €209.00
Special Price Starting at:
€190.00
G-479 is an potent MEK inhibitor. G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects. ...
Special Price Starting at: €190.00
Special Price Starting at:
€68.40
Triciribine phosphate inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation. ...
Special Price Starting at: €68.40
Special Price Starting at:
€94.05
SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively. ...
Special Price Starting at: €94.05
Special Price Starting at:
€190.00
SR-13668 is an Akt inhibitor, is also an orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic and ...
Special Price Starting at: €190.00
Special Price Starting at:
€304.00
ARQ 092 is an oral activie, potent and selective AKT inhibitor with IC50 values: 5.0 nM (AKT1); 4.5 nM (AKT2); 16 nM (AKT3). ...
Special Price Starting at: €304.00
Special Price Starting at:
€34.20
PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays, 100-fold more selective for MEK1/2 than MEK5. Phase 2. ...
Special Price Starting at: €34.20
Special Price Starting at:
€76.95
AKT inhibitor VIII is a cell-permeable and reversible quinoxaline compound that potently and selectively inhibits Akt1/Akt2 activity (IC50 = 58 nM, 210 nM, and 2.12 ?M for Akt1, Akt2, and Akt3, respec ...
Special Price Starting at: €76.95
Special Price Starting at:
€72.68
Triciribine, also known as API-2, suppresses the phosphorylation level and kinase activity of Akt. ...
Special Price Starting at: €72.68
Special Price Starting at:
€89.78
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well a ...
Special Price Starting at: €89.78
Special Price Starting at:
€88.07
CCT128930 is an ATP-competitive AKT inhibitor that is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA, achieved by targeting a single amino acid difference. ...
Special Price Starting at: €88.07
Special Price Starting at:
€68.40
GDC-0068 is a selective, ATP-competitive, pan-Akt inhibitor that targets Akt1, 2, and 3 with IC50 values of 5, 18, and 8 nM, respectively in cell-free assays ...
Special Price Starting at: €68.40
Special Price Starting at:
€171.00
GNE-493 is potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitor with potential anticancer activity. ...
Special Price Starting at: €171.00
Special Price Starting at:
€142.50
PD 334581 is used in biological studies to evaluate halogen bonding as a novel interaction for rational drug design. It is also an inhibitor of MEK1. ...
Special Price Starting at: €142.50
Special Price Starting at:
€47.50
PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase. ...
Special Price Starting at: €47.50
Special Price Starting at:
€85.50
PD318088 is an inhibitor of MEK1 AND MEK2. ...
Special Price Starting at: €85.50
Special Price Starting at:
€72.68
Arctigenin is an antioxidant, anti-inflammatory, antiproliferative and antiviral agent. It inhibits LPS-induced iNOS expression via inhibition of IκBα phosphorylation and p65 nuclear translocation ( ...
Special Price Starting at: €72.68
Special Price Starting at:
€152.00
AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively, little activity outside the AGC kinase family. ...
Special Price Starting at: €152.00
Special Price Starting at:
€64.13
GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively). ...
Special Price Starting at: €64.13
Special Price Starting at:
€102.60
Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively for MEK1 over MEK2 and showed no significant inhibition when ...
Special Price Starting at: €102.60
Special Price Starting at:
€85.50
Refametinib is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
...
Special Price Starting at: €85.50
Special Price Starting at:
€133.00
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1. ...
Special Price Starting at: €133.00
Special Price Starting at:
€60.80
AZD6244 (Selumetinib) also known as Selumetinib, ARRY142886, AZD-6244 & ARRY-142886 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm. ...
Special Price Starting at: €60.80
Special Price Starting at:
€76.95
TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. ...
Special Price Starting at: €76.95
Keywords:buy Honokiol | Honokiol Supplier | purchase Honokiol | Honokiol cost | Honokiol manufacturer | order Honokiol | Honokiol distributor | buy 35354-74-6| 35354-74-6 Supplier | purchase 35354-74-6 | 35354-74-6 cost | 35354-74-6 manufacturer | order 35354-74-6 | 35354-74-6 distributor
We Using Safe Payments:
