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Cenisertib (AS-703569) is a multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.15 mL | 110.73 mL | 221.46 mL |
| 0.5 mM | 4.43 mL | 22.15 mL | 44.29 mL |
| 1 mM | 2.21 mL | 11.07 mL | 22.15 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.43 mL |
*The above data is based on the productmolecular weight 451.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11262 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 871357-89-0 |
| Formula | C24H30FN7O |
| M. Wt | 451.54 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | AS-703569; R-763 |
| SMILES | [H][[email protected]@]1([[email protected]]([[email protected]]2C(N)=O)NC3=NC(NC4=CC=C(C(C)=C4)N5CCN(CC5)C)=NC=C3F)C[[email protected]]2(C=C1)[H] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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