Cenisertib

Catalog No.: A11262

multi-kinase inhibitor

Cenisertib

Cenisertib Chemical Structure

CAS NO. 871357-89-0

Cenisertib (AS-703569) is a multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3.

Availability: In stock

Package Price Qty
5 mg
$288.00
10 mg
$496.00
50 mg
$1,472.00
100 mg
$2,944.00
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Biological Activity

Cenisertib (AS-703569) is a multi-kinase inhibitor that blocks the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5 and FLT3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.15 mL 110.73 mL 221.46 mL
0.5 mM 4.43 mL 22.15 mL 44.29 mL
1 mM 2.21 mL 11.07 mL 22.15 mL
5 mM 0.44 mL 2.21 mL 4.43 mL

*The above data is based on the productmolecular weight 451.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11262
Actions Inhibitor
CAS No. 871357-89-0
Formula C24H30FN7O
M. Wt 451.54
Solubility DMSO
Purity >98%
Synonyms AS-703569; R-763
SMILES [H][[email protected]@]1([[email protected]]([[email protected]]2C(N)=O)NC3=NC(NC4=CC=C(C(C)=C4)N5CCN(CC5)C)=NC=C3F)C[[email protected]]2(C=C1)[H]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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