Signaling Pathway
Important Notice: For research use only. We do not sell to patients.
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| Discription | AZD5363 is a potent inhibitor of AKT with pharmacodynamic activity in vivo, has potential to treat a range of solid and hematologic tumors as monotherapy or a combinatorial agent. | |||||
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| Cell Research |
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| Catalog Num | A11759 |
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| Formula | C21H25ClN6O2 |
| Molecular Weight | 428.9 |
| CAS Number | 1143532-39-1 |
| SMILES | C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
| Synonyms | AZD 5363, AZD-5363 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 79 mg/mL (184.18 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.32 mL | 116.58 mL | 233.15 mL |
| 0.5 mM | 4.66 mL | 23.32 mL | 46.63 mL |
| 1 mM | 2.33 mL | 11.66 mL | 23.32 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
