Afuresertib

Catalog No.: A16392

Akt inhibitor

Afuresertib Chemical Structure

CAS NO. 1047644-62-1

Afuresertib is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.

Availability: In stock

Package Price Qty
5 mg
$75.00
10 mg
$105.00
50 mg
$295.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Afuresertib is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.4 mL 117.01 mL 234.02 mL
0.5 mM 4.68 mL 23.4 mL 46.8 mL
1 mM 2.34 mL 11.7 mL 23.4 mL
5 mM 0.47 mL 2.34 mL 4.68 mL

*The above data is based on the productmolecular weight 427.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16392
Actions Inhibitor
M. Wt 427.32
Formula C18H17Cl2FN4OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1047644-62-1
Synonyms GSK 2110183, GSK2110183, GSK-2110183
SMILES CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)NC(CC3=CC(=CC=C3)F)CN)Cl

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