Guggulsterone
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. | ||
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Catalog Num | A19825 |
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Formula | C21H28O2 |
Molecular Weight | 312.45 |
CAS Number | 95975-55-6 |
SMILES | C[C@@]1(/C2=C/C)[C@](CC2=O)([H])[C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])CC1 |
Synonyms | Z/E-Guggulsterone |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 55 mg/mL (176.03 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.01 mL | 160.03 mL | 320.05 mL |
0.5 mM | 6.4 mL | 32.01 mL | 64.01 mL |
1 mM | 3.2 mL | 16 mL | 32.01 mL |
5 mM | 0.64 mL | 3.2 mL | 6.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2