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$0.00 E3 Ligase Ligands
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E3 ligase Ligand 9
Catalog No. A19051 E3 ubiquitin ligase ligandE3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 9 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. Learn More -
E3 ligase Ligand 10
Catalog No. A19045 E3 ubiquitin ligase ligandE3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. Learn More -
E3 ligase Ligand 14
Catalog No. A19028 E3 ubiquitin ligase ligandE3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. Learn More -
BC-1215
Catalog No. A18605 FBXO3 inhibitorBC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg/mL for IL-1β release). BC-1215 decreases Fbxo3-Fbxl2 interaction and prevents SCFFbxo3 catalyzed Fbxl2 ubiquitination. Learn More -
TD-106
Catalog No. A18595 CRBN modulatorTD-106 is a cereblon (CRBN) modulator, which can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation. Learn More -
VH032-cyclopropane-F
Catalog No. A18417 VH032-based VHL ligandVH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). Learn More -
Thalidomide fluoride
Catalog No. A12144 Thalidomide-based Cereblon ligandThalidomide fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966). Learn More
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