Thalidomide-NH-CH2-COOH

Catalog No.: A30235
Ligands for E3 Ligase
Thalidomide-NH-CH2-COOH is a Thalidomide-derived ligand that specifically targets the cereblon (CRBN) protein, facilitating its recruitment in various biological processes. This compound serves as a crucial building block for the development of PROTACs, allowing researchers to design targeted protein degradation strategies. Its application is significant in the study of protein homeostasis and the therapeutic potential of targeted protein modulation.
Grouped product items
Size Price Stock Qty
10mg
$25.00
In stock
250mg
$85.00
In stock
500mg
$135.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-NH-CH2-COOH is a Thalidomide-derived ligand that specifically targets the cereblon (CRBN) protein, facilitating its recruitment in various biological processes. This compound serves as a crucial building block for the development of PROTACs, allowing researchers to design targeted protein degradation strategies. Its application is significant in the study of protein homeostasis and the therapeutic potential of targeted protein modulation.
Product Information
Catalog NumA30235
FormulaC15H13N3O6
Molecular Weight331.28
CAS Number927670-97-1
SMILESO=C(O)CNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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