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Biological Activity
E3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.77 mL | 73.87 mL | 147.75 mL |
| 0.5 mM | 2.95 mL | 14.77 mL | 29.55 mL |
| 1 mM | 1.48 mL | 7.39 mL | 14.77 mL |
| 5 mM | 0.3 mL | 1.48 mL | 2.95 mL |
*The above data is based on the productmolecular weight 676.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A19028 |
|---|---|
| CAS No. | 2241489-43-8 |
| Formula | C38H52N4O7 |
| M. Wt | 676.84 |
| Purity | >98% |
| SMILES | O=C(N[C@@H]1CCCC2=C1C=CC=C2)[C@H]3N(C[C@H](C3)OC4=CC=CC(O)=C4)C([C@@H](NC([C@H](C)N(C(OC(C)(C)C)=O)C)=O)C5CCCCC5)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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