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(Rac)-Spirotetramat-enol

Ligands for E3 Ligase

(Rac)-Spirotetramat-enol serves as a ligand for E3 ligases, demonstrating significant potential in targeted protein degradation research. Primarily involved in the modulation of acetyl-CoA carboxylase, this compound facilitates the synthesis of PROTAC ADC degraders. Its application in the development of innovative therapeutic strategies underscores its importance in chemical biology and drug discovery.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	382608-09-5
Applications	Ligands for E3 Ligase
Formula	C₁₈H₂₃NO₃
Molecular Weight	301.38
SMILES	O=C1NC2(CCC(CC2)OC)C(O)=C1C3=C(C)C=CC(C)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.