(Rac)-Spirotetramat-enol

Catalog No.: A43950
Ligands for E3 Ligase
(Rac)-Spirotetramat-enol serves as a ligand for E3 ligases, demonstrating significant potential in targeted protein degradation research. Primarily involved in the modulation of acetyl-CoA carboxylase, this compound facilitates the synthesis of PROTAC ADC degraders. Its application in the development of innovative therapeutic strategies underscores its importance in chemical biology and drug discovery.
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(Rac)-Spirotetramat-enol serves as a ligand for E3 ligases, demonstrating significant potential in targeted protein degradation research. Primarily involved in the modulation of acetyl-CoA carboxylase, this compound facilitates the synthesis of PROTAC ADC degraders. Its application in the development of innovative therapeutic strategies underscores its importance in chemical biology and drug discovery.
Product Information
Catalog NumA43950
FormulaC18H23NO3
Molecular Weight301.38
CAS Number382608-09-5
SMILESO=C1NC2(CCC(CC2)OC)C(O)=C1C3=C(C)C=CC(C)=C3
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