XB2M54

Catalog No.: A35648
Ligands for E3 Ligase
XB2M54 is a selective antagonist of X-linked inhibitor of apoptosis protein (XIAP), functioning as a ligand for E3 ligases. It effectively inhibits NOD2-mediated inflammatory signaling pathways, making it a valuable tool in inflammation research. Additionally, XB2M54 can be employed in the synthesis of PROTAC ERα Degrader-1, facilitating studies on targeted protein degradation and its implications in therapeutic applications.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXB2M54 is a selective antagonist of X-linked inhibitor of apoptosis protein (XIAP), functioning as a ligand for E3 ligases. It effectively inhibits NOD2-mediated inflammatory signaling pathways, making it a valuable tool in inflammation research. Additionally, XB2M54 can be employed in the synthesis of PROTAC ERα Degrader-1, facilitating studies on targeted protein degradation and its implications in therapeutic applications.
Product Information
Catalog NumA35648
FormulaC29H31N5O4
Molecular Weight513.59
CAS Number1467165-30-5
SMILESCN[C@H](C(N[C@@H]1C(N(C2=C(N([C@H]1C)C(C)=O)C=C(C#N)C=C2)CC3=C(C=CC4=C3C=CC=C4)OC)=O)=O)C
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