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VH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.77 mL | 93.87 mL | 187.75 mL |
| 0.5 mM | 3.75 mL | 18.77 mL | 37.55 mL |
| 1 mM | 1.88 mL | 9.39 mL | 18.77 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.75 mL |
*The above data is based on the productmolecular weight 532.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18417 |
|---|---|
| CAS No. | 2306193-99-5 |
| Formula | C26H33FN4O5S |
| M. Wt | 532.63 |
| Purity | >98% |
| Synonyms | VHL ligand 3; E3 ligase Ligand 19 |
| SMILES | O=C(NCC1=CC=C(C=C1O)C2=C(N=CS2)C)[[email protected]]3N(C[[email protected]@H](C3)O)C([[email protected]](C(C)(C)C)NC(C4(CC4)F)=O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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