Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide derivative that functions as a ligand for the E3 ubiquitin ligase Cereblon (CRBN). By recruiting CRBN proteins, this compound is a critical intermediate in the development of CRBN-based PROTAC molecules. These PROTACs are engineered to selectively target and degrade the SHP2 protein, making them valuable tools for cancer research and therapeutic applications.
Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide derivative that functions as a ligand for the E3 ubiquitin ligase Cereblon (CRBN). By recruiting CRBN proteins, this compound is a critical intermediate in the development of CRBN-based PROTAC molecules. These PROTACs are engineered to selectively target and degrade the SHP2 protein, making them valuable tools for cancer research and therapeutic applications.
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