Biological Activity
PROTAC CRBN Degrader-1 comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group. PROTAC CRBN Degrader-1 is an cereblon (CRBN) degrader.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 9.42 mL | 47.11 mL | 94.23 mL |
0.5 mM | 1.88 mL | 9.42 mL | 18.85 mL |
1 mM | 0.94 mL | 4.71 mL | 9.42 mL |
5 mM | 0.19 mL | 0.94 mL | 1.88 mL |
*The above data is based on the productmolecular weight 1061.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18863 |
---|---|
Actions | Degrader |
CAS No. | 2358775-70-7 |
Formula | C53H72N8O13S |
M. Wt | 1061.25 |
Purity | >98% |
Synonyms | 0 |
SMILES | O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCNC(COCCCCCOCCOCCCCCOCC(N[[email protected]@H](C(C)(C)C)C(N4C[[email protected]](O)C[[email protected]]4C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)=O)=O)=O)=CC=C3)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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