Thalidomide-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
Thalidomide-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
Targets
Target
Value
Product Information
Catalog Num
A20259
Formula
C13H10N2O5
Molecular Weight
274.23
CAS Number
5054-59-1
SMILES
OC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
Synonyms
Cereblon ligand 2; E3 ligase Ligand 2
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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