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E3 ligase Ligand 36

E3 Ligase Ligand

E3 Ligase Ligand 36 is a potent E3 ligase ligand that serves as a key substrate for the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates targeted protein degradation and has been utilized in the development of PROTAC BRM/BRG1 degrader-1. This compound provides valuable tools for research in protein regulation and therapeutic applications in various diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3031995-12-4
Applications	E3 Ligase Ligand
Formula	C₂₅H₃₀N₄O₅S
Molecular Weight	498.59
SMILES	OC1=NOC([C@@H](C(C)C)C(N2C[C@H](O)C[C@H]2C(N[C@@H](C)C3=CC=C(C4=C(C)N=CS4)C=C3)=O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.