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| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| HCC827 | IC50 | > 10 μM | Antiproliferative activity against human HCC827 cells harboring EGFRDel19 mutant assessed as reduction in cell viability incubated for 72 hrs by MTT assay | [PMID: 31951960] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 1448297-52-6 |
| Formula | C22H30N4O3S |
| Molecular Weight | 430.567 |
| Synonyms | MDK7526; Protein degrader 1; VHL Ligand 1; ULM-1; VH032 desacetyl; VH032 amine; Degradation Inducing Moiety A |
| SMILES | O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2 |
No reported solubility data are available for this product.
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
