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Publications citing Adooq Products
Chemical Information
| Catalog Num | A13590 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 381.3 |
| Formula | C20H25ClN2OHCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 925681-41-0 |
| Synonyms | Akt Inhibitor X |
| SMILES code | CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl |
| Chemical Name | 2-chloro-N,N-diethyl-10H-phenoxazine-10-butanamine, monohydrochloride |
Description |
10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. | |||||
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