10-DEBC HCl

AKT/PKB inhibitor‎

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Catalog No. A13590

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
10-DEBC HCl 10mg A13590-10

Regular Price: $100.00

Special Price: $85.00

10-DEBC HCl 25mg A13590-25

Regular Price: $200.00

Special Price: $170.00

10-DEBC HCl 50mg A13590-50

Regular Price: $320.00

Special Price: $272.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 ??M), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein.

10-DEBC HCl

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Chemical Information

Catalog Num A13590
Actions Inhibitor
M. Wt 381.3
Formula C20H25ClN2OHCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 925681-41-0
Synonyms Akt Inhibitor X
SMILES code CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl
Chemical Name 2-chloro-N,N-diethyl-10H-phenoxazine-10-butanamine, monohydrochloride

Biological Activity

Description
10-DEBC HCl is a selective inhibitor of Akt/PKB. It inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 ??M), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein.

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