A 803467 Sodium channel Blocker

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Catalog No. A11234

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
A 803467 10mg A11234-10
$50.00
A 803467 25mg A11234-25
$98.00
A 803467 50mg A11234-50
$150.00
A 803467 100mg A11234-100
$250.00
A 803467 10mM * 1mL in DMSO A11234-10mM-D
$77.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

A 803467 is a selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively).

A 803467

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Chemical Information

Catalog Num A11234
Actions Blocker
M. Wt 357.8
Formula C19H16ClNO4
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 944261-79-4
Synonyms A-803467, A803467
SMILES code COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC
Chemical Name 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide

Biological Activity

Description
A 803467 is a selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively).
Targets
Na(V1.8) channel
8 nM

Solubility

Solubility (25°C) * In vitro DMSO 72 mg/mL (201.23 mM)
Water <1 mg/mL (<1 mM)
Ethanol 11 mg/mL (30.74 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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