Abiraterone (CB-7598)

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CYP17 inhibitor

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Catalog No. A10020

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Abiraterone 5mg A10020-5

Regular Price: $40.00

Special Price: $34.00

Abiraterone 10mg A10020-10

Regular Price: $50.00

Special Price: $42.50

Abiraterone 50mg A10020-50

Regular Price: $60.00

Special Price: $51.00

Abiraterone 100mg A10020-100

Regular Price: $80.00

Special Price: $68.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.

Abiraterone (CB-7598)

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Chemical Information

Catalog Num A10020
Actions Inhibitor
M. Wt 349.2
Formula C24H31NO
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 154229-19-3
Synonyms CB-7598, CB7598
SMILES code C[[email protected]]12CC[[email protected]@H](CC1=CC[[email protected]@H]3[[email protected]@H]2CC[[email protected]]4([[email protected]]3CC=C4C5=CN=CC=C5)C)O
Chemical Name (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol

Biological Activity

Description
Abiraterone (CB-7598) inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1), an enzyme which is expressed in testicular, adrenal, and prostatic tumor tissues.
Targets
CYP17 (Cell-free assay)
2 nM

Solubility

Solubility (25°C)* In vitro DMSO 0.1 mg/mL (<1 mM)
Water 0.02 mg/mL (<1 mM)
Ethanol 0.2 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

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